BACKGROUND It has been proposed that the expired-air carbon monoxide (CO) threshold for confirming smoking abstinence in clinical practice be reduced below 10 ppm. Optimal thresholds may vary across regions. Data are needed to assess the impact of such a change on claimed success. METHODS A total of 253 smokers who attended the Tanglin quit smoking clinic in Malaysia were followed-up 1, 3 and...

AIM A study was undertaken to investigate the effect of organic zinc (zinc nicotinate, Zn-nic) supplementation (6, 9, and 12 ppm) compared to inorganic zinc (12 ppm) on growth performance, hematology, serum biochemical constituents oxidative stress, and immunity in weaned female Sprague-Dawley rats. MATERIAL AND METHODS A 48 weaned rats (285.20±1.95 g) were randomly distributed to 4 dietary t...

Stewart LT. Cell adhesion proteins and the pathogenesis of autism spectrum disorders. J Neurophysiol 113: 1283–1286, 2015. First published July 2, 2014; doi:10.1152/jn.00780.2013.—Current theories on the pathogenesis of autism spectrum disorders (ASD) maintain that the associated cognitive and behavioral symptoms are caused by aberrant synaptic transmission affecting specific brain circuits. Tr...

BACKGROUND We recently reported that valve prosthesis-patient mismatch (PPM) is associated with persisting pulmonary hypertension after mitral valve replacement. Thus, the objective of this study was to evaluate the impact of PPM on mortality in patients undergoing mitral valve replacement. METHODS AND RESULTS The indexed valve effective orifice area was estimated for each type and size of pr...

We report high resolution solution (19)F NMR spectra of fluorine-labeled rhodopsin mutants in detergent micelles. Single cysteine substitution mutants in the cytoplasmic face of rhodopsin were labeled by attachment of the trifluoroethylthio (TET), CF(3)-CH(2)-S, group through a disulfide linkage. TET-labeled cysteine mutants at amino acid positions 67, 140, 245, 248, 311, and 316 in rhodopsin w...

We evaluated the effect of several compounds on their ability to reduce the production of sul®de in in vitro ruminal fermentations, when sulfur content of the diet was 1% (dry matter basis). Excess sulfur increased (p<0.05) ruminal sul®de production, but had no effects on VFA production. The effect of 1, 10 and 25 ppm ( ̄uid basis) of 9,10 anthraquinone (AQ) and molybdenum in high sulfur diets w...

BACKGROUND Permanent pacemaker (PPM) implantation after cardiac surgery is required in 0.4-6% of patients depending on cardiac surgery type. PPM implantation in the early postoperative period may reduce morbidity and postoperative hospital stay. We performed a retrospective review of electronic medical records of adult patients with coronary artery bypass grafting (CABG), valve surgery, or both...

BACKGROUND Surface microhardness is a physical property which access the effect of chemical and physical agents on hard tissues of teeth, and a useful way to examine the resistance of fluoride treated enamel against caries. The purpose of this study was to evaluate microhardness of enamel following pH-cycling through demineralization and remineralization using suspensions of dentifrices with di...