5-Diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311 (NSC-645809), is an antitumor agent shown to be effective against breast cancer in phase II clinical trials. A similar compound, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone, C-1305, shows high activity against experimental tumors and is expected to have even more beneficial pharmacological properties than C-1311. Previously ...

Abstract Background PrEP (Pre-Exposure Prophylaxis) is a strategy that involves combination of antiretrovirals medications aimed to reduce HIV transmission among at-risk individuals. The purpose this quality improvement project increase internal medicine residents' knowledge and prescribing PrEP. Methods We administered an anonymous paper survey residents at all stages training our suburban com...