A close examination of the hands of people depicted in paintings of the Flemish school showed that in five paintings there were figures with hand lesions resembling those of rhematoid arthritis. Although none of the deformities or swellings are indisputable examples of rheumatoid arthritis, they do at least suggest that the painters must have been confronted with rheumatoid-like lesions in thei...

Wide Field Camera 3 (WFC3) is a general-purpose imager in development for installation in HST Servicing Mission 4 (SM4). Covering the wavelength range of 200-1700 nm in two observing channels, WFC3 offers powerful new capabilities, particularly in the near-ultraviolet and near-infrared bands. During 2004, the instrument was integrated and underwent a substantial suite of end-to-end characteriza...

We present a low-loss, compact, polarization insensitive 3-dB optical power-splitter for submicron silicon waveguides. The splitter is optimized over broad wavelength span ranging from 1300 to 1700 nm through finite difference time domain simulations. junction footprint only 1.8 × 1.3 ?m, which smaller than previously reported broadband multimode splitters. Furthermore, the demonstrated device ...

The proper design of a product life cycle may contribute both to the optimization of primary raw material usage and to the reduction of waste environmental impacts. Recycling may enter the life cycle of products in the contexts of production of secondary raw materials and reduction of waste extensive disposal in landfills. Tradition plants for plastic separation in homogeneous products employ m...

Ras malignant transformation requires posttranslational modification by farnesyltransferase (FTase). Here we report on the design and antitumor activity, in monotherapy as well as in combination therapy with cytotoxic agents, of a novel class of non-thiol-containing peptidomimetic inhibitors of FTase and the closely related family member geranylgeranyltransferase I (GGTase I). The non-thiol-con...

Geography Unit, Department of Geosciences, University of Fribourg, Chemin du Musée 4, CH-1700 Fribourg, Switzerland Chair for Climatic Change and Climate Impacts, Institute for Environmental Sciences, University of Geneva, Route de Drize 7, CH-1227 Carouge, Switzerland c Laboratory of Dendrogeomorphology, Institute of Geological Sciences, University of Bern, Baltzerstrasse 1-3, CH-3012 Bern, Sw...

In a typical forensic investigation, fabric analysis plays vital role in solving different crimes. Several types of textile fibre materials (cotton, polyester, denim, polypropylene, polycotton, and viscose) were analysed the presence common contaminants (blood, rainwater, seawater, sand gunshot-residue) to evaluate performance two NIR spectrometers for situ crime scene conditions. The used SCIO...

a University of Fribourg, Physics Department, Perolles, CH-1700 Fribourg, Switzerland b Empa, Swiss Federal Laboratories for Materials Testing and Research, Laboratory for Hydrogen and Energy, Überlandstrasse 129, CH-8600 Dübendorf, Switzerland c University of Fribourg, Department of Geoscience, Perolles, CH-1700 Fribourg, Switzerland d Instituto de Ciencia de Materials de Madrid, Cantoblanco, ...

The existing methods for detection of the cloud scenes are applied at relatively small spectral range within shortwave upwelling radiative wavelength flux. We have reported a new method based on Radiance Enhancement (RE). This can be used to cover significantly wider from 1100 nm 1700 by using datasets space-orbiting micro-spectrometer Argus 1000. Due high sunlight reflection smoke originated f...