BACKGROUND This study evaluated the effect of omeprazole or pantoprazole on platelet reactivity in non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients receiving clopidogrel. METHODS Consecutive patients with NSTE-ACS (n = 620) from general hospital of Shenyang Military Command were randomized to the omeprazole or pantoprazole (20 mg/d) group (1:1), and received routine dual a...

BACKGROUND Heart failure (HF) with preserved ejection fraction (HFpEF) is more common in women than in men; data characterizing sex differences in the management and outcomes of HFpEF patients presenting to the emergency department (ED) are limited. METHODS AND RESULTS Using Acute Decompensated Heart Failure National Registry Emergency Module data linked to Medicare claims, we conducted a ret...

BACKGROUND The incidence of Clostridium difficile-associated disease (CDAD) is increasing. There are few data on the short-term and long-term attributable costs of CDAD. The objective of this study was to determine the acute and 180-day attributable inpatient costs of CDAD. METHODS We performed a retrospective cohort study of all patients without operating room costs who were admitted for > o...

BACKGROUND AND PURPOSE Studies on the relation between blood pressure (BP) and stroke outcome have shown contradictory results. We explored the association of systolic (SBP) and diastolic (DBP) BP during acute stroke with early neurological deterioration, infarct volume, neurological outcome, and mortality at 3 months. METHODS We included 304 patients with acute ischemic stroke. SBP and DBP o...

= Abstract =The purpose of this study is to evaluate the possibility of application of SRCA to previously frozen tumor tissue. Mouse sarcoma-180 and human squamous cell carcinoma of the uterine cervix were used as implanting tumor specimens. The fresh tumor specimens were frozen by rapid freezing method and stored in a liquid nitrogen tank. On the 7th day of freezing, the specimens were thawed ...

The best entertainment for the younger generation now is given in the form of Social Networking sites. The Online Social Networks (OSN) mainly helps an individual to connect with their friends, family and the society online in order to gather and share new experiences with others. Nowa-days, the OSNs are facing the problem of the people posting the indecent messages on any individual's wall whi...

We present a brief report on the factorization of RSA-180, currently smallest unfactored RSA number. We show that the numbers of similar size could be factored in a reasonable time at home using open source factoring software running on a few Intel Core i7 PCs.

The 180 models collected in this paper are produced by sampling and wrapping point sets on tubes. The surfaces are represented as triangulated 2-manifolds and available as stlfiles from the author’s web site at www.cs.duke.edu/ edels. Each tube is obtained by thickening a circle or a smooth torus knot, and for some we use the degrees of freedom in the thickening process to encode meaningful inf...

In applications of NMR in inhomogeneous fields, sequences based on the Carr-PurcellMeiboom-Gill (CPMG) sequence play a central role. The standard CPMG sequence consists of an initial 90° excitation pulse, followed by a long string of 180° refocusing pulses. This creates a series of echoes that decay with characteristic relaxation time T2eff. Here we present a modified sequence, the Split-180° s...

Laninamivir octanoate (LO) (Inavir; Daiichi Sankyo, Japan) is an ester prodrug of the neuraminidase inhibitor laninamivir. We previously reported that a prolonged high retention of laninamivir in mouse respiratory tissues was achieved by intranasal administration of LO. In this study, we evaluated intrapulmonary pharmacokinetics both in vivo and in vitro to investigate the potential mechanism i...