Eleven samples containing various amounts of simmondsin (S), simmondsin ferulate (SF), demethyl simmondsins (DMS) and didemethyl simmondsins (DDMS) were analyzed by five different laboratories. The samples were made from chromatographically pure simmondsin, animal feed formulations containing jojoba meal, defatted jojoba meal, water extracts of jojoba meal and combinations of these ingredients....

Abstract We present and analyze the dataset on international distribution of industrial robots by country, industry, application provided International Federation Robotics (IFR) since 1993. After describing IFR we point out specificities limitations its dataset. explain process data collection, develop a correspondence table between industry classification ISIC rev. 4 classification, clarify ap...

Plasmids and cloning cDNA for human USP4 and USP8 was a gift from Hidde Ploegh and cDNA for USP39 was a gift from R. Medema. USP4CD (aa 296-954) and the D1 fragment (aa 296-490) of human USP4, USP39CD (aa 219-565) and USP8CD (aa 771-1118) were cloned using ligation independent cloning into pET-46 Ek/LIC vector (Novagen). The D2 fragment (aa 766-932) of USP4 was cloned into the pET-NKI b/3C (Lun...

In this thesis, we propose a set of tools for the statistical quanti cation and com-parison of asymmetry within a population or between two populations of structuresrepresented by 3D point sets. These tools are designed in a coherent framework relyingon a modeling of the point sets as mixtures of probability density functions dependingon parameters describing for example a re ec...

[1] Dimethylsulphide (DMS) is a climatically important component of global biogeochemical cycles, through its role in the sulphur cycle. Changes in ultraviolet radiation (UV) exhibit both positive and negative forcings on the dynamics of production and turnover of DMS and its precursor dimethylsulphoniopropionate (DMSP). In this study we investigate the net forcing of UV on atmospheric DMS. The...

For decades, dimethyl sulfate (DMS) mapping has informed manual modeling of RNA structure in vitro and in vivo. Here, we incorporate DMS data into automated secondary structure inference using an energy minimization framework developed for 2'-OH acylation (SHAPE) mapping. On six noncoding RNAs with crystallographic models, DMS-guided modeling achieves overall false negative and false discovery ...

N,N-Dimethyl-D-erythro-sphingosine (DMS) is known to induce cell apoptosis by specifically inhibiting sphingosine kinase 1 (SPHK1) and modulating the activity of cellular ceramide levels. The present study investigated the effects and the mechanism(s) of action of DMS in human lung cancer cells. We found that DMS dose-dependently suppressed cell proliferation and induced cell apoptosis in the h...