Hepatic parenchymal cells from adult rats, established in vitro as a monolayer, have been evaluated by electron microscopy . Within 24 h after the initial seeding, the incubated cells were polygonal and in close apposition with three to six neighboring cells . The ultrastructure of the monolayer cells was examined at this time and after 3 and 10 days of incubation . With the exception of a few ...

We evaluated whole body and regional (subcutaneous abdominal adipose tissue and forearm) norepinephrine (NE) kinetics in seven lean (body mass index 21.3 ± 0.5 kg/m2) and six upper body obese (body mass index 36.4 ± 0.4 kg/m2) women who were matched on fat-free mass. NE kinetics were determined by infusing [3H]NE and obtaining blood samples from a radial artery, a deep forearm vein draining mos...

The term higher gauge theory refers to the generalization of gauge theory to a theory of connections at two levels, essentially given by 1and 2-forms. So far, there have been two approaches to this subject. The differential picture uses non-Abelian 1and 2-forms in order to generalize the connection 1-form of a conventional gauge theory to the next level. The integral picture makes use of curves...

The sorting of membrane-bound proteins from the trans-Golgi network to lysosomal/endosomal compartments is achieved by preferential inclusion into clathrin-coated vesicles. Contained within the cytoplasmic domains of such proteins, specific sequence motifs have been identified (tyrosine-based and/or di-leucine-based) that are essential for targeting and are recognized by a family of heterotetra...

The resolution of almost all conventional optical system is indispensably governed by the diffraction limit. This resolution limit can be overcome by use of focusing the evanescent waves in the near field region. The concept of “superlens” was proposed firstly by Pendry in 2000 [1]. When ε= -1and μ= -1, the negative refractive index material plate can be a perfect lens [2-4]. Because of the dis...

Objective: To explore and summarize the effect of sirolimus on ischemic-type biliary lesions (ITBL) after liver transplantation. Methods: A retrospective study was carried out on 52 patients using sirolimus for biliary complications after liver transplantation from 2004 to 2016 in our hospital. Serum alanine transaminase (ALT), aspartate transaminase (AST), total bilirubin, glutamyl endopeptida...

Four variables mean brood size, day of first reproduction, longevity and per capita rate of increase ( r ) -were compared in four 70-d chronic toxicity tests in which Daphnia pulex were exposed to cadmium or copper in continuous and pulsed exposures. With these data we asked the question: Is the population-level variable ( r ) more sensitive than the three organism-level variables (mean brood s...

in this paper, we discuss the geometric properties of solution and lower bound estimate of ∆um−1 of the cauchy problem for a degenerate parabolic equation with periodic source term ut =∆um+ upsint. our objective is to show that: (1)with continuous variation of time t, the surface ϕ = [u(x,t)]mδq is a complete riemannian manifold floating in space rn+1and is tangent to the space rn at ∂h0(t); (2...

With a 3.3-V interface, such as PCI-X application, high-voltage overstress on the gate oxide is a serious reliability problem in designing I/O circuits by using only 1/2.5-V low-voltage devices in a 0.13m CMOS process. Thus, a new output buffer realized with low-voltage (1and 2.5-V) devices to drive high-voltage signals for 3.3-V applications is proposed in this paper. The proposed output buffe...

A novel, simple and economic reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the estimation of zolpidem tartrate in bulk and tablet dosage form with greater precision and accuracy. Separation was achieved on C18 column (250X4.6mm i.d.,5μm) in isocratic mode using methanol and acetonitrile in the ratio 50:50 (v/v) as mobile phase, pumped in to the col...