Chem. Abstr. Serv. Reg. No.: 126-07-8 Deleted CAS Nos: 8027-03-0; 8055-10-5; 3426-54-8; 11103-62-1; 24659-79-8 Chem. Abstr. Name: (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione IUPAC Systematic Name: 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione Synonyms: (2S,4′R)-7-Chloro-2′,4,6-trimethoxy-4′-methyl...

We have studied the developmental changes of glutamate-induced calcium (Ca²⁺) response in primary cultured hippocampal neurons at three different stages of cultures, 3, 7-8, and 14-16 days in vitro (DIV), using fura-2 single-cell digital micro-fluorimetry. We found that glutamate-induced Ca²⁺ signaling was altered during development, and that two different ionotropic glutamate receptors, α-amin...

dione); 1 1flOH-P (1 1/?-hydroxyprogesterone; 1 1 /?-hydroxypregn-4ene-3,20-dione); 1 I-0x0-P (1 1-oxoprogesterone; pregn-4-ene-3,11,20trione); 21-d-F (2 I-deoxycortisol; 11/?,17a-dihydroxypregn-4-ene-3,20dione); 2 1 -d-E (2 1-deoxycortisone; 17a-hydroxypregn-4-ene-3,11,20trione); 1 1-deoxycortisol (Reichstein’s substance S ; cortexolone; 1 7 ~ 2 l-dihydroxypregn-4-ene-3,20-dione); DHS (dihydro...

Intra and intermolecular interactions found in the developed crystals of synthesized py-ron-2,4-dione derivatives play crucial rules molecular conformations crystal stabili-ties, respectively. In this regard, Hirshfeld calculations were used to quantitatively analyze different structures some functionalized py-ran-2,4-dione derivatives. The X-ray structure pyran-2,4-dione derivative namely (3E,...

Selective induction of apoptosis in cancer cells barring the normal cells is considered as an effective strategy to combat cancer. In the present study, a series of twenty-two (22) synthetic 3,3'-(aryl/alkyl-methylene)bis(2-hydroxynaphthalene-1,4-dione) bis-lawsone derivatives were assayed for their pro-apoptotic activity in six different cell lines (five cancerous and one normal) using MTT ass...