نتایج جستجو برای: 2 inhibitors
تعداد نتایج: 2655500 فیلتر نتایج به سال:
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two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic human alveolar basal epithel...
Inhibition performances of imidazoline derivatives with different alkyl chain length for carbon steel in H2S acid solutions has been studied by polarization curves, AC impedance measurements, current transient, Atomic Force Microscopy (AFM) and Density Functional Theory (DFT) techniques. Results showed that the inhibition occurs through adsorption of the inhibitors molecules ...
Introduction Thyroid cancer is a malignant disease with poor prognosis. The PI3K/Akt/mTOR and Cyclin-Dependent Kinase 4 (CDK4) pathways are vital regulators of tumor cell proliferation and survival. Therefore the present study was designed to use dual inhibition of such pathways to kill thyroid cancer cells. Methods and materials The effects of each inhibitors on human ATC and...
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