Abstract Gluten-free beer (GFB) was produced from gluten-containing barley malt wort by adding an enzyme-enriched extract to the wort, intended for patients with celiac disease. Nevertheless, aroma profile of such is unknown. The results indicated that treatment reduced 3-methylbutyl acetate, 2-methylbutyl ethyl hexanoate, 2-methylpropyl and butyrate when compared reference. Moreover, foam, fre...

We observed previously that glucose deprivation induces cytotoxicity, increases the intracellular levels of hydroperoxide, and activates the stress-activated protein kinase (SEK) pathway. In this study, we hypothesized that 1-methylpropyl 2-imidazolyl disulfide (IV-2), a thioredoxin (TRX) inhibitor, augments glucose deprivation-induced cytotoxicity by promoting c-Jun N-terminal kinase (JNK) act...

1-Methylpropyl 2-imidazolyl disulfide (PX-12) has been proposed as an inhibitor of thioredoxin-1 (Trx-1) with antitumor activity. However, the antitumor activity of the Trx-1 redox signaling inhibitor PX-12 on colorectal cancer is still obscure. In the present study, we showed that PX-12 inhibited the growth of colorectal cancer DLD-1 and SW620 cells in a dose- and time-dependent manner. Furthe...

The chemistry of the iron complexes of two Schiff-base ligands namely, N-2-mercaptophenyl-20-pyridylmethylenimine (PyASH, 1) and N-2-mercapto-2-methylpropyl-20-pyridylmethylenimine (PyMSH, 2) has been explored in a systematic manner. Use of DMF as solvent allows one to isolate the Fe(II) complexes in pure forms. The Fe(III) complexes [Fe(PyAS)2]X (X ˆ BF4, BPh4 (3)) and [Fe(PyMS)2]BPh4 (4) have...

OBJECTIVE To assess the clinical and molecular response of patients with recurrent high-grade vulvar, vaginal, or cervical intraepithelial neoplasia treated with topical 1-2(2-methylpropyl)-1H-imidazo [4,5-c] quinolin-4-amine (imiquimod) cream 5%, an immune response modifier with known efficacy in the treatment of external genital warts. METHODS This is the first case series in the peer-revie...

Technetium 99m-hexakis-2-methoxy-2-methylpropyl-isonitrile (Tc-MIBI) is a promising new myocardial perfusion imaging agent producing excellent rest images. Imaging, however, will need to be performed with exercise or dipyridamole to detect ischemia and to differentiate salvaged but still ischemic myocardium from scar. Accordingly, 12 dogs were given mild-to-moderate left circumflex coronary ste...

BACKGROUND Fatty acids occur in nearly all living organisms as the important predominant constituents of lipids. While all fatty acids have essentially the same chemical nature, they are an extremely diverse group of compounds. MATERIALS AND METHODS To test the hypothesis, fatty acids of alkaliphiles isolates, Bacillus subtilis SVUNM4, Bacillus licheniformis SVUNM8, Bacillus methylotrohicus S...