نتایج جستجو برای: 2 substituted 4

تعداد نتایج: 3138588  

The resistance of antimicrobials has become a global hazard with the irrational use of antibiotics. Infection of drug-resistance bacteria seriously threatens human health. Currently there is an urgent need for the development of novel antimicrobial agents with new mechanisms and lower levels of toxicity. In this paper, a series of (S,Z)-4-methyl-2-(4-oxo-5-((5-substitutedphenylfuran-2-yl) methy...

Journal: :The Journal of the Society of Chemical Industry, Japan 1967

The resistance of antimicrobials has become a global hazard with the irrational use of antibiotics. Infection of drug-resistance bacteria seriously threatens human health. Currently there is an urgent need for the development of novel antimicrobial agents with new mechanisms and lower levels of toxicity. In this paper, a series of (S,Z)-4-methyl-2-(4-oxo-5-((5-substitutedphenylfuran-2-yl) methy...

2015
Sunil Kumar Hemlata Kaur Indu Singh Monica Sharma Pinki Vishwakarma K. K. Saxena

A Series of 3-Substituted phenyl 2-(3,4-dihydroxyphenyl ethyl amino)-6-substituted quinazolin-4-(3H) ones (4a-4h) have been synthesized by the reaction of 3-Substituted phenyl -2-methylbromo-6-substituted quinazolin-4-(3H) ones (3a-3h) with dopamine (3,4 dihydroxy phenyl ethyl amine). The biological screening showed that compound 4f namely 3-(2-Chloro phenyl)2-(3, 4-dihydroxyphenyl ethyl amino)...

Journal: :iranian journal of pharmaceutical research 0
nb patel vn patel

synthesis of 2-[2-(2,6-dichlorophenyl)amino]phenylmethyl-3-[4-(2-substitutedphenyl-4-oxo-thiazolidinyl)aryl]-6-bromo quinazolin-4(3h)ones via-j have been achieved from the starting material 2-[(2,6-dichlorophenyl)amino] phenylacetic acid i to benzoxazine iii, further reaction with p-phenylindiamine and substituted aromatic aldehyde gave 2-[2-(2,6-dichlorophenyl)amino]phenyl methyl-3-(4-aminoary...

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