objective: the effect of interleukin (il)-29, a new therapeutic agent similar to type i interferons (ifns), on ifn-α secretion of human plasmacytoid dendritic cells (pdcs) has not been studied. therefore, in this study, we aimed to clarify the effect of il-29 on ifn-α secretion of pdcs using human peripheral blood mononuclear cells (pbmcs) in the presence of cytosine-phosphate-guanosinemotif-co...

introduction: today, due to the broad spectrum of pediatric cancers are treated by the chemotherapy drugs, but these drugs have side effects and gastrointestinal toxicity is the most prevalent. one of the main roles of nurses is to better health through patient education and care for him. evidence-based nursing is a process during which the nurse can use the available research evidence, their c...

The Tn antigen, which arises from mutation in the Cosmc gene is one of the most common tumor associated carbohydrate antigens. Cosmc resides in X24 encoded by a single gene and functions as a specific molecular chaperone for T-synthase. While the Tn antigen cannot be detected in normal cells, Cosmc mutations inactivate T-synthase and consequently result in Tn antigen expression within certain c...