The NoC is a specific flavour of interconnection networks. Interconnection networks have been studied for more than two decades and a solid foundation of design techniques is available. We will give a short introduction to the terminology, principles, theory of interconnection networks that are relevant for this thesis. Furthermore, we describe specific characteristics of NoCs in comparison wit...

The recent advances in IC technology have made it possible to implement systems with dozens or even hundreds of cores in a single chip. With such a large number of cores communicating with each other there is a strong pressure over the communication infrastructure to deliver high bandwidth, low latency, low power consumption and quality of service to guarantee real-time functionality. Networks-...

The Network-on-Chip (NoC) approach for designing (System-on-Chip) SoCs is currently used for overcoming the scalability and efficiency problems of traditional on-chip interconnection schemes, such as shared buses and point-to-point links. NoC design draws on concepts from computer networks to interconnect Intellectual Property (IP) cores in a structured and scalable way, promoting design re-use...

As technology scales down, the interconnect for on-chip global communication becomes the delay bottleneck. In order to provide well-controlled global wire delay and efficient global communication, a Network-on-Chip (NoC) architecture was proposed by different authors [Route packets, not wires: on-chip interconnection networks, in: Design Automation Conference, 2001, Proceedings, p. 684; Network...

We previously demonstrated that 5,7-dihydroxy-8-nitrochrysin (NOC), a novel synthetic chrysin analog, preferentially inhibits HER-2/neu-overexpressing MDA-MB-453 breast cancer cell growth by inducing apoptosis; however, the precise molecular mechanism was unclear. In this study, we demonstrated that NOC significantly induces apoptosis of MDA-MB-453 cells and that this is primarily mediated thro...

Stimulated human neutrophils exhibit increased net oxygen consumption (NOC) due to the conversion of O2 into the superoxide anion by the NADPH oxidase enzymatic complex during the respiratory burst. In several inflammatory diseases, overproduction of these oxidants causes tissue damage. The present study aims to: (a) optimize the experimental conditions used to measure the NOC in serum-opsonize...

The variety of interconnection structures presently nowadays for SoC (System-on-Chip), bus and networkson-Chip NoCs, each of them with a wide set of setup parameters, provides a huge amount of design alternatives. Although the interconnection structure is a key SoC component, there are few design tools in order to set the appropriate configuration parameters for a given application at the first...

Increasing heterogeneous software and hardware blocks constitute complex ICs known as System on Chip (SoC). These blocks are conceived as intellectual property (IP) cores. Designers are developing SoCs by using IP cores reuse, which include interconnection architecture and interface to peripheral devices.Because of the SoC growing complexity, some researchers tend to concentrate more on the com...

Application mapping is one of the key problems of Network-on-Chip (NoC) design. It maps the cores of application to the processing elements of the NoC topology. This paper presents a novel approach for NoC application mapping, which uses adaptive genetic algorithm (AGA) in the mapping. The proposed approach adaptively varies the probabilities of crossover and mutation operators in genetic algor...

Experimental approaches used for architecture exploration and validation are often based on configurable logic device such as FPGA. NoC architectures require multi-FPGA platforms as the resources of a single FPGA are not big enough. Partitionning a NoC on multi-FPGA requires special techniques for allocating communication channels, physical links and suitable resource allocation scheme. We pres...