With the objective of finding valuable herbicidal candidates, a series of new 5-heterocycloxy-3-methyl-1-substituted-1H-pyrazoles were synthesized and their herbicidal activities were evaluated. The bioassay results showed that some compounds exhibited excellent herbicidal activities at the concentration of 100 mg/L, and compound 5-chloro-2-((3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl)ox...

a series of curcumin derivatives containing heterocyclic moiety have been synthesized and evaluated for their antibacterial activities. the chemical structures of the synthesized compounds were verified on the basis of spectral data and elemental analyses. investigation of antimicrobial activity of the derivatives demonstrated the ability to inhibit gram-positive microorganisms with zone of inh...

A novel series of 7,7-diphenyl-1,2-dihydroimidazo[2,1-c][1,2,4]triazin-6(7H)-one 6a-h, were easily prepared via reactions of novel 2-hydrazinyl-4,4-diphenyl-1H-imidazol-5(4H)-one (2) with hydrazonoyl halides 3a-h. In addition, we also examined the reaction of compound 2 with commercially available active methylene compounds to afford new pyrazoles containing an imidazolone moiety, expected to b...

The α-arylation of cyclic and fluoroalkyl 1,3-diketones is made challenging by the highly stabilized nature corresponding enolates, especially difficult for sterically demanding aryl partners. As a general solution to this problem, we report Bi-mediated oxidative coupling acidic diones ortho-substituted arylboronic acids. Starting from bench-stable bismacycle precursor, sequence B-to-Bi transme...

Synthesis of di-pyrrolyl-substituted pyrazoles (dpp) and anion binding studies in protonated form are reported. Dpp show [2 + 2] binding of trifluoroacetate in the solid state to afford nanometer- and micrometer-scale architectures.