Self-assembly of a binary mixture of poly(styrene)336-block-poly(4-vinyl pyridine)25 (PS336-b-P4VP25) and poly(ethylene glycol)113-block-poly(4-hydroxy styrene)25 (PEG113-b-P4HS25) is shown to give rise to a cylindrical morphology in thin films through pyridine/phenol-based hetero-complementary hydrogen bonding interactions between the P4VP and P4HS copolymer segments. Removal of the cylindrica...

Background: The study of possible ways effective correction retinal ischemia-reperfusion injury, which accompanies a number eye diseases, is relevant today. aim the study: To retinoprotective effect and antiapoptotic mechanism 2-Ethyl-3-hydroxy-6-methyl-pyridine-N-acetyltaurinate (EHMP-NAT) in rat model ischemia–reperfusion (I/R). Materials methods: A pathology with an increase intraocular pres...

In this study, we characterized a muscarinic acetylcholine receptor (mAChR) potentiator, LY2119620 (3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide) as a novel probe of the human M2 and M4 allosteric binding sites. Since the discovery of allosteric binding sites on G protein-coupled receptors, compounds targeting these novel ...

In the title compound, C(7)H(6)ClN(3)O(4)S(2)·3C(5)H(5)N, (systematic name: 6-chloro-2H-1,2,4-benzothia-diazine-7-sulfonamide 1,1-dioxide pyridine tris-olvate), chloro-thia-zide forms a 1:3 solvate with pyridine. The crystal structure is stabilized by strong inter-molecular N-H⋯N hydrogen bonds.

The title compound, C(6)H(8)N(3) (+)·Cl(-), crystallizes with two formula units in the asymmetric unit. The cations are non-planar with the -C(NH(2))(2) groups twisted relative to the ring planes by 36.7 (3) and 37.8 (3)°. The cations are linked into chains through N-H⋯N hydrogen bonds. N-H⋯Cl hydrogen bonds link the chains into a three-dimensional network.

In the title compound, C(11)H(9)ClN, the dihedral angle between the aromatic ring planes is 44.2 (1)° and the bridging C-N-C bond angle is 127.60 (19)°. The amino N-H grouping makes a hydrogen bond to the pyridyl N atom of an adjacent mol-ecule across a center of inversion, generating a hydrogen-bonded dimer.