Raising public awareness of organ donation is high on the national agenda, but the magnitude of the challenge is not well clarified. We investigated the attitudes and experience of general practitioners (GPs) regarding organ donation. A survey of 200 GPs working in Ireland revealed that a minority provided donor cards (38%) or displayed information regarding organ donation (28.2%). Although 81....

Organ-transplant recipients have an elevated risk of keratinocyte cancers: basal cell carcinoma (BCC) and squamous carcinoma. We assessed whether polygenic scores (PRSs) generated in nontransplantees from the UK Biobank 23andMe (13,981 carcinoma, 33,736 BCC, >560,000 controls) can predict cancer independent organ-transplant recipient cohort. After adjusting for traditional factors, compared wit...

Background:  This study presents patient specific and organ dose estimation in computed tomography (CT) imaging of thorax directly from patient CT image using Monte Carlo simulation.  Patient's CT image is considered as the patient specific phantom and the best representative of patient physical index in order to calculate specific organ dose. Materials and Methods: EGSnrc /BEAMnr...

STUDY OBJECTIVES To determine the circulating anti-inflammatory cytokine interleukin 10 (IL-10) response during the development of sepsis-induced multiple organ failure in children. DESIGN Prospective study. SETTING University pediatric ICU. PATIENTS Fifty-three consecutive children with sepsis and 15 critically ill children without sepsis. INTERVENTIONS Plasma IL-10, interleukin 6 (IL-...

OBJECTIVE To identify the independent variables associated with death within 4 days after the first sepsis-induced organ dysfunction. METHODS In this prospective observational study, severe sepsis and septic shock patients were classified into 3 groups: Group 1, survivors; Group 2, late non-survivors; and Group 3, early non-survivors. Early death was defined as death occurring within 4 days a...

In order to examine the effect of the quantity of Nitrogen fertilizer and bush density on vegetative and productive function of henna medicinal plant (Lawsonia inermis)  factorial experimentation in the form of block plan was carried in three stages in agriculture research center in south of kerman  province in corp of 2012. The first factor containing Nitrogen fertilizer in 4 levels i...

Thymus is a lymphoid organ which has endocrine function [3]. It also plays a very important role in the immune system [1]. The organ is situated in the ventral part of the cranial mediastinum, between the first and sixth intercostal space, on the sternum [4, 11]. The organ consists of two yellowish lobes, one is named right lobe, the other left lobe. [3, 8, 11, 17]. In the newborn animals it is...

OBJECTIVES We hypothesize that three inflammation pathobiology phenotypes are associated with increased inflammation, proclivity to develop features of macrophage activation syndrome, and multiple organ failure-related death in pediatric severe sepsis. DESIGN Prospective cohort study comparing children with severe sepsis and any of three phenotypes: 1) immunoparalysis-associated multiple orga...

A simple multiple system organ failure (MSOF) score may predict mortality of patients who have sepsis syndrome. Using an MSOF scoring system, we prospectively determined the presence or absence of respiratory, cardiovascular, renal, hepatic, gastrointestinal, hematologic, and neurologic organ failure on day 1 of sepsis syndrome in 154 consecutive patients who had sepsis syndrome in the ICU of a...