Draft Agreed by Pharmacogenomics Working Party and EWPPK March 2010 Adoption by CHMP for release for consultation 22 April 2010 End of consultation (deadline for comments) 31 October 2010 Agreed by Pharmacogenomics Working Party October 2011 Adoption by CHMP 19 January 2012 Date for coming into effect 1 August 2012 This guideline replaces the Reflection Paper on the use of Pharmacogenetics in t...

Received: 28 February 2005 Revised: 31 October 2005 2nd Revision: 31 March 2005 Accepted: 2 October 2006 Abstract This study examines a strategic development and implementation process of enterprise content management (ECM) in a large oil company. In view of the framework of four motors of development and change in organizations, this study represents a revelatory case of a hybrid development a...

There is a worldwide increase in the incidence of type 1 diabetes (1–3). This increase, in conjunction with the lack of complete concordance in monozygotic twin pairs, points to the importance of environmental factors (3). Useful clues about these environmental factors may be obtained by studying geographical variation in incidence in relation to the characteristics of different countries. Ther...

s related to the thesis: I. Poreisz C, Antal A, Brepohl N, Boros K, Csifcsák G, Paulus W. Transcranial direct current stimulation over somatosensory cortex decreases experimentally induced pain perception. Seventh Göttingen Meeting of the German Neuroscience Society. Göttingen, Germany, March 29 April 1, 2007. II. Csifcsák G, Antal A, Paulus W. Modulatory effects of transcranial direct current ...

background: since the mortality rate of mothers and infants is due to preventable factors, this study aimed to determine the effects of interventions on decreasing the mortality rate of pregnant women in isfahan province, iran. methods: this was an interventional study. the study population included all dead mothers in isfahan province from 21 march 2002 to 20 march 2005 and after intervention ...

BACKGROUND Reduction of neonatal mortality rate can improve health and newborn status of the society. This study was done to evaluate the prevalence and pattern of causes for neonatal mortality in Gorgan, North of Iran. METHODS this descriptive, cross-sectional study was carried out on all birth in the maternity Dezyani hospital in Gorgan, North of Iran during 1 September 2008 -31 March 2011....

INTRODUCTION Febrile seizure (FS) is the most common paediatric neurological problem. The purpose of this study was to determine the frequency of afebrile seizures subsequent to FS in children with initial FS and to evaluate its risk factors. METHODS A prospective study was conducted on all children (age 6 months to 6 years) referred with initial FS to the Shahid Sadoughi Hospital, Yazd, Iran...

Acknowledgments This work was supported by Swiss National Science Foundation grants #31-63894.00 and #3100A0-103993/1. We thank Prof. G.M. Innocenti for helpful comments and valuable suggestions, and Ms. D. Polzik for assistance in the preparation of the manuscript. We are grateful to our peer-reviewers for their meaningful comments on the manuscript. MK and EF contributed equally to this work....