CONTEXT High intakes of fat and specific fatty acids, including total, animal, saturated, polyunsaturated, and trans-unsaturated fats, have been postulated to increase breast cancer risk. OBJECTIVE To determine whether intakes of fat and fatty acids are associated with breast cancer. DESIGN AND SETTING Cohort study (Nurses' Health Study) conducted in the United States beginning in 1976. P...

The interaction of dietary fat and the thymus in the induction of mammary tumors by dimethylbenz(a)anthracene has been examined in female Sprague-Dawley rats. In these experiments, rats fed diets of 0.5% (low fat), 5% (normal fat), or 20% (high fat) corn oil from weaning (21 days of age) were thymectomized or sham thymectomized at 35 days of age and were given 5 mg of dimethylbenz(a)anthracene ...

OBJECTIVE To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine. MATERIALS AND METHODS Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDE...

This study compared the effect of prolonged moderate-intensity continuous training (MICT) on reducing abdominal visceral fat in obese young women with that of work-equivalent (300 kJ/training session) high-intensity interval training (HIIT). Forty-three participants received either HIIT (n = 15), MICT (n = 15), or no training (CON, n = 13) for 12 weeks. The abdominal visceral fat area (AVFA) an...

We recently characterised Sprouty1 (Spry1), a growth factor signalling inhibitor as a regulator of marrow progenitor cells promoting osteoblast differentiation at the expense of adipocytes. Adipose tissue-specific Spry1 expression in mice resulted in increased bone mass and reduced body fat, while conditional knockout of Spry1 had the opposite effect with decreased bone mass and increased body ...

The effect of the level of fat substitution in cakes as well as the type of fat replacer on the textural behaviour of the product was investigated by instrumental and sensory analysis. Samples, which were varying in levels (35, 65 and 100%) and types (carbohydrate or protein based) of fat substitution were subjected to a compression test and the obtained stress strain, sigmoid curves were fitte...

BACKGROUND The amount of body fat, rather than the amount of excess weight, determines the health risks of obesity, type 2 diabetes mellitus, and cardiovascular disease. AIMS To look at the association of body fat percentage with cardiometabolic risk factors in subjects with normal glucose tolerance (NGT). SETTINGS AND DESIGN Cross-section study from the Chennai Urban Rural Epidemiology Stu...

Aim: Fat oxidation is impaired in obesity. The aim of this study was to determine if fat oxidation, seen in a high protein meal response, was influenced by body composition. Methods: Subjects were provided with control (14% protein, glycemic index, GI 65), high protein high GI (33% protein, GI 74), and high protein low GI (35% protein, GI 45) meals. Substrate oxidation and energy expenditure we...

BACKGROUND Cactus (Opuntia ficus-indica) fiber was shown to promote weight loss in a 3-month clinical investigation. As demonstrated by in vitro studies, cactus fiber binds to dietary fat and its use results in reduced absorption, which in turn leads to reduced energy absorption and ultimately the reduction of body weight. OBJECTIVE The objective of our study was to elucidate the dietary fat ...

W e read with interest the article by Freire et al. (1), which implicates that total dietary fat might increase the risk for metabolic syndrome. Conversely, they discovered an inverse relationship between linoleic acid intake and the metabolic syndrome. These data add to the mounting evidence describing the association between high dietary fat intake and features of metabolic syndrome either al...