miRNAs are small RNA molecules binding to partially complementary sites in the 3 -UTR of target transcripts and repressing their expression. miRNAs orchestrate multiple cellular functions and play critical roles in cell differentiation and cancer development. We analyzed miRNA profiles in B-cell subsets during peripheral B-cell differentiation as well as in diffuse large B-cell lymphoma (DLBCL)...

Two new nuclear equations of state (EOSs) are proposed and are applied to neutron star (NS). They predict the incompressibilitiesK0 = 179MeV and 230MeV, respectively. The density dependencies of nuclear symmetry energies are consistent with the recent analyses of heavy-ion reactions. We can reproduce the recently observed super-massive NS of MG > 2:5M , the mass-radius relation of EXO 0748-676 ...

In the ROSAT Bright Survey (RBS) we have almost completely optically identified the brightest ∼2000 high-galactic latitude sources from the ROSAT All-Sky Survey Bright Source Catalogue (1RXS). A small number of sources has empty X-ray error circles on optical images. ROSAT HRI follow-up observations of RBS1223 (=1RXS J130848.6+212708), a soft object with extreme X-ray to optical flux ratio, hav...

The necessary and sufficient condition for dynamical stability is worked out for the sequences of relativistic star models corresponding to the well defined and causal values of adiabatic sound speed, √ (dP/dE)0 = v0, at the centre. On the basis of these conditions, we show that the mass-radius (M −R) relation corresponding to the MIT bag models of strange quark matter (SQM) and the models obta...

The cooling history of a quark star in the 2-flavour color superconductive (2SC) phase is investigated. In particular the novel process of photon generation via glueball (GLB) decay in the 2SC phase is taken into account. As much as 10−10 erg of energy is provided by the GLB decay. This source of photons fundamentally intrinsic to quark matter in the 2SC phase is unique to our model. The genera...

As shown recently by Kaminker et al. (2001), current observations of thermal emission of isolated middle–aged neutron stars (NSs) can be explained by cooling of NSs of different masses with the cores composed of neutrons, protons and electrons, assuming rather strong superfluidity (SF) of protons, weak triplet-state SF of neutrons and neglecting singlet-state SF of neutrons. We show that this e...

OBJECTIVE Women with primary ovarian insufficiency (POI) present an increased risk for cardiovascular disease. In this study we tested the hypothesis that POI in women under hormone therapy (HT) are associated with vascular vasodilatation attenuation and cardiovascular autonomic dysfunction and these impairments are related to changes in systemic antioxidant enzymes. Furthermore, the possibilit...

Recently, observations of compact stars have provided new data of high accuracy which put strong constraints on the high-density behaviour of the equation of state of strongly interacting matter otherwise not accessible in terrestrial laboratories. The evidence for neutron stars with high mass (M = 2.1±0.2M⊙ for PSR J0751+1807) and large radii (R > 12 km for RX J1856-3754) rules out soft equati...

A new scheme for testing the nuclear matter (NM) equation of state (EoS) at high densities using constraints from compact star (CS) phenomenology is applied to neutron stars with a core of deconfined quark matter (QM). An acceptable EoS shall not to be in conflict with the mass measurement of 2.1 ± 0.2 M⊙ (1 σ level) for PSR J0751+1807 and the mass-radius relation deduced from the thermal emiss...

As shown recently by Kaminker et al. (2001), current observations of thermal emission of isolated middle-aged neutron stars (NSs) can be explained by cooling of NSs of different masses with the cores composed of neutrons, protons and electrons, assuming rather strong superfluidity (SF) of protons, weak triplet-state SF of neutrons and neglecting singlet-state SF of neutrons. We show that this e...