OBJECTIVE The aim of this study was to evaluate the potential of (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET) for monitoring the therapeutic efficacy of TAK-733, an inhibitor of mitogen-activated protein kinase kinase, in nude rats bearing A549 (human lung carcinoma) xenografts. METHODS TAK-733 was administered orally by gavage to nude xenograft rats for 2 weeks, at d...

background: acyclovir (acv), a synthetic purine nucleoside analogue, is known to be toxic to gonads. objective: the current study evaluated cytotoxicity of acv on histopathological changes in testis tissue and serum testosterone and lipid peroxidation concentrations of male rats. materials and methods: animals were divided into five groups. one group served as control and one group served as co...

Sumac (Rhus coriaria L.), belonging to the Anacardiaceae family, grows in Mediterranean countries, North Africa, South Europe, Afghanistan and Iran. The sumac berries contain biological activities such as antioxidant, antimicrobial, hypoglycemic and antidiabetic. The present study examined the effects of water extract of sumac on the chemical, microbiological and sensory quality on silver carp ...

— The paper shows that the current view of globalization as an automatic and benign force is flawed: it focuses on only one, positive, face of globalization while entirely neglecting the malignant one. The two key historical episodes that are adduced by the supporters of the ‘‘globalization as it is’’ (the Halcyon days of the 1870–1913, and the record of the last two decades of development) are...

The conversion of alpha-linolenate (18:3n-3) to docosahexaenoate (22:6n-3) in the presence of low and high dietary levels of linoleate (18:2n-6) is reported in young rats using [U-13C]-alpha-linolenic acid (18:2n-3*) and high precision gas chromatography-combustion isotope ratio mass spectrometry (GCC-IRMS). After consuming an 18:3n-3-deficient diet for 4 weeks, dams were bred and assigned to o...

PURPOSE To evaluate the relation between statin therapy, vascular endothelial growth factor (VEGF) expression, vascular leakage, and CNV size in experimentally induced choroidal neovascularization (CNV). METHODS Wild-type (C57 Bl/6J) mice received pitavastatin 0.18 mg/kg per day (group 1), 1.8 mg/kg per day (group 2) or 18 mg/kg per day (group 3) for 3 days before laser-induced CNV and contin...

Spontaneous conjunctival folliculosis, a disease widespread among rabbits, has been described in a preceding article (1) as occurring in two clinical forms, Type I and Type II . The former is characterized by a dormant chronicity with discrete lesions, whereas the second type, a more act ively progressive disease, presents an inf lammatory follicular reaction involving all the palpebral conjunc...

ferula foetida (bunge) regel. is one of the most widespread and important ferula species with nutritional and medicinal applications. some phytochemicals with helpful cardiovascular effects have been isolated from ferula species. the present study was designed to evaluate the effects of hydroalcoholic extract of the stems of f. foetida in dexamethasone (dex)-induced hypertension in rats. hypert...

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in this research, buffalo production was studied from view points of housing, feeding, milk production and reproducrion in rural area of shoushtar, khuzestan. the results of this study revealed that in a herd 66.7 , 8.3 and 25 % were breeders (adult females), adult bulls and valves. each breeder female buffalo had 3-17 parturation in whole life. first service was done at 18 month after birth an...