The novel organic salt 7-((5-bromo-1H-indol-3-yl)(4-methoxyphenyl)methyl)1,3,5-triaza-7-phosphaadamantan-7-ium tetrafluoroborate was synthesized from a Lewis acid (LA) and Lewis-base (LB) reaction between 1,3,5-triaza-7-phosphaadmantane 5-bromo-3-(4-methoxybenzylidene)-3-H-indol-1-ium (LA). obtained base adduct, being the title compound, analyzed validated by 1H, 13C, 31P, 19F 1D-NMR-spectrosco...

Transient stimulation of group I metabotropic glutamate receptors (mGluRs) induces persistent prolonged epileptiform discharges in hippocampal slices via a protein synthesis-dependent process. At present, the signaling process underlying the induction of these epileptiform discharges remains unknown. We examined the possible role of extracellular signal-regulated kinases (ERK1 and ERK2) because...

extended abstract 7-4

Minor products in the reaction between substituted 1,3-diiminoisoindolines and 2,5-diamino-3,4-dicyanothiophene were identified as the nickel seco-tribenzoporphyrazines 4 and 5, which have been characterized by UV-vis, MCD, NMR, and mass spectroscopy. Experimentally observed tetraazachlorin-type UV-vis spectra of new seco-tribenzoporphyrazines were explained on the basis of DFT and TDDFT calcul...

In the title salt, C(5)H(8)N(3) (+)·C(6)H(7)O(2) (-), the pyridine N atom of the 2,3-diamino-pyridine mol-ecule is protonated. The 2,3-diamino-pyridinium cation is essentially planar, with a maximum deviation of 0.068 (2) Å for one of the amino N atoms. The sorbate anion adopts an extended conformation. In the crystal structure, the protonated N atom and one of the two amino-group H atoms are h...

The nitroaromatic compound TNT is a common component in military munitions because of its chemical stability and comparatively safe method of manufacture. In living systems, TNT is rapidly metabolized into four identifi able and extractable compounds (2-amino-4,6dinitrotoluene, 4-amino-2,6-dinitrotoluene, 2,4-diamino-6-nitrotoluene, and 2,6-diamino-4-nitrotoluene). Exposing model organisms to T...

Silica sodium carbonate (SSC) has been used as a valuable silica-supported catalyst for the preparation of a range of known and novel pyrano coumarins via the three-component reactions of aryl aldehydes, active methylene compound (malononitrile or ethyl cyanoacetate), and hydroxycoumarin (5,7-dihydroxy-4-substituted coumarins or 4-hydroxycoumarin). The heterogeneous catalyst showed much the sam...

The title compound, C(12)H(14)ClN(4) (+)·C(9)H(8)NO(3) (-), is a salt with a 1:1 ratio of cation and anion components inter-acting with each other forming an R(2) (2)(8) ring motif. The crystal structure is stabilized by hydrogen bonds (N-H⋯O) involving two different eight-membered rings. One of them is formed between the pyrimidine ring (donor) and the carboxylate group (acceptor) from the ben...