DAVID J. LEFER,1 STEVEN P. JONES,1 WESLEY G. GIROD,1 AMARPREET BAINES,3 MATTHEW B. GRISHAM,1 ADAM S. COCKRELL,1 PAUL L. HUANG,2 AND ROSARIO SCALIA3 1Department of Molecular and Cellular Physiology, Louisiana State University Medical Center, Shreveport, Louisiana 71130; 2Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129; and 3Department of Physiolog...

CONSUELO PLATA,1 DAVID B. MOUNT,2 VERENA RUBIO,1 STEVEN C. HEBERT,2 AND GERARDO GAMBA1 1Molecular Physiology Unit, Department of Nephrology and Mineral Metabolism, Instituto Nacional de la Nutrición Salvador Zubirán and Department of Medicine, Instituto de Investigaciones Biomédicas, National University of Mexico, Mexico City CP 14000, Mexico; and 2Division of Nephrology, Department of Medicine...

S. TAHERZADEH,1 S. SHARMA,1 V. CHHAJLANI,2 I. GANTZ,3 N. RAJORA,1 M. T. DEMITRI,4 L. KELLY,1 H. ZHAO,1 T. ICHIYAMA,1 A. CATANIA,4 AND J. M. LIPTON1,5 Departments of 1Physiology and 5Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235-9040; 2Astra Hassle, 431 83 Molndal, Sweden; 3Department of Surgery, University of Michigan Medical ...

Lutz, Peter L., and Liscia Manuel. Maintenance of adenosine A1 receptor function during long-term anoxia in the turtle brain. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R633–R636, 1999.—It has been established that adenosine has a critical role in the extraordinary ability of the turtle brain to survive anoxia. To further investigate this phenomenon we compared rat and turt...

Keep, Richard F., Xiaochen Si, Parvin Shakui, Steven R. Ennis, and A. Lorris Betz. Effect of amiloride analogs on DOCA-salt-induced hypertension in rats. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H2215–H2220, 1999.—Intracerebroventricular infusions of an amiloride analog, benzamil, reduce blood pressure in several rat models of hypertension. This effect has been attributed to an inhibition...

Berry, Susan A., Pearl L. Bergad, Allison M. Stolz, Howard C. Towle, and Sarah Jane Schwarzenberg. Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation: discordant responses to IL-6. Am. J. Physiol. 276 (Cell Physiol. 45): C1374–C1382, 1999.—The rat serine protease inhibitor (Spi) 2 gene family includes both positive (Spi 2.2) and negative (Spi 2.1) acute phase reactants,...

Doughty, Joanne M., Frances Plane, and Philip D. Langton. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1107–H1112, 1999.—In rat mesenteric artery, endothelium-derived hyperpolarizing factor (EDHF) is blocked by a combination of apamin and charybdotoxin (ChTX). The site of action of these t...

Oyekan, A. O., K. McAward, J. Conetta, L. Rosenfeld, and John C. McGiff. Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCAsalt hypertension. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R766–R775, 1999.—Inhibition of cytochrome P-450 (CYP450) enzymes with cobalt chloride (CoCl2) prevented hypertension, organ hypertrophy, and renal inju...

Chang, Hangil, and Toshiro Fujita. A numerical model of the renal distal tubule. Am. J. Physiol. 276 (Renal Physiol. 45): F931–F951, 1999.—A numerical model of the rat distal tubule was developed to simulate water and solute transport in this nephron segment. This model incorporates the following: 1) Na-Cl cotransporter, K-Cl cotransporter, Na channel, K channel, and Cl channel in the luminal m...

There is considerable inter-individual variability in self-selected intensity or running speed. Metabolic cost per distance has been recognized as a determinant of this personal choice. As biomechanical parameters have been connected to metabolic cost, and as different running patterns exist, we can question their possible determinant roles in self-selected speed. We examined the selfselected s...