The purpose of this study was to investigate the capability Streptococcus thermophilus TISTR 458 on hyaluronic acid (HA) production by using various carbon sources including glucose, sucrose and sugarcane molasses. HA determined a turbidity assay precipitation with cetyltrimethylammonium bromide (CTAB) sugar content analysed sulphuric acid-UV spectrophotometry method. results showed that S. pro...

BACKGROUND This meta-analysis compared clinical outcomes of arthroplasty vs. osteosynthesis for displaced femoral neck fractures. METHODS Meta-analysis was performed on the difference in revision rate and overall mortality between participants undergoing osteosynthesis vs. total hip arthroplasty (THA), osteosynthesis vs. hemiarthroplasty (HA), or THA vs. HA. RESULTS Pooled direct and indire...

Tacrine (THA) and physostigmine (PHS) have been used in Alzheimer's disease therapy for their anticholinesterasic activity. Here we show that THA is taken up in rat lysosomes in an energy-dependent manner, and that it is also accumulated in acidic compartments of rat thymocytes and neuroblastoma cells. A concentration of THA less than 1 mM dissipated the pH gradient (delta pH) in all the above ...

Total hip arthroplasty (THA) has been shown to be highly effective in ameliorating pain and increasing function in adults with end stage arthritis of the hip. Early studies of cemented THA in children with advanced hip disease reported poor results, but, more recently, results of cementless THA show greatly improved outcomes. More recently, concerns related to THA in children have focused on we...

Corticosteroid-binding globulin (CBG) delivers anti-inflammatory cortisol to inflamed tissues upon elastase-based proteolysis of the exposed reactive center loop (RCL). However, the molecular mechanisms that regulate the RCL proteolysis by co-existing host and bacterial elastases in inflamed/infected tissues remain unknown. We document that RCL-localized Asn(347) glycosylation fine-tunes the RC...

PURPOSE Periprosthetic joint infection (PJI) after total hip arthroplasty (THA) is a grave complication. Urinary tract infection (UTI) as a source for PJI is controversial. Our purposes were, (1) to evaluate the incidence of PJI after elective primary THA and (2) to determine whether UTI was associated with a risk of PJI after elective primary THA. MATERIALS AND METHODS We retrospectively rev...

PURPOSE It remains controversial whether mini-incision (MI) benefits patients in total hip arthroplasty (THA). We performed a meta-analysis of randomized controlled trials (RCTs) to assess the effects of MI on surgical and functional outcomes in THA patients. METHODS A systematic electronic literature search (up to May 2013) was conducted to identify RCTs comparing MI with standard incision (...

BACKGROUND Demand for total hip arthroplasty (THA) is high and expected to continue to grow during the next decade. Although much of this growth includes working-aged patients, cost-effectiveness studies on THA have not fully incorporated the productivity effects from surgery. QUESTIONS/PURPOSES We asked: (1) What is the expected effect of THA on patients' employment and earnings? (2) How doe...