Baldwin, Ann L. Modified hemoglobins produce venular interendothelial gaps and albumin leakage in the rat mesentery. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H650– H659, 1999.—Cross-linked hemoglobin (aa-Hb) and polyethylene glycol (PEG)-conjugated Hb have both been considered as possible ‘‘blood substitutes.’’ Previously, we showed that PEG-Hb extravasates rapidly in the intestinal mucos...

Richard, C. A., D. M. Rector, R. K. Harper, and R. M. Harper. Optical imaging of the ventral medullary surface across sleep-wake states. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1239–R1245, 1999.—We hypothesized that spontaneous activity declines over widespread areas of the cat ventral medullary surface (VMS) during rapid eye movement (REM) sleep. We assessed neural and...

Schwartz, Lisa M., Thomas R. Bukowski, James H. Revkin, and James B. Bassingthwaighte. Cardiac endothelial transport and metabolism of adenosine and inosine. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1241–H1251, 1999.—The influence of transmembrane flux limitations on cellular metabolism of purine nucleosides was assessed in whole organ studies. Transcapillary transport of the purine nucl...

Dong, Sheng-Jing, Paul S. Hees, Wen-Mei Huang, Sam A. Buffer, Jr., James L. Weiss, and Edward P. Shapiro. Independent effects of preload, afterload, and contractility on left ventricular torsion. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H1053–H1060, 1999.—Shortening of oblique left ventricular (LV) fibers results in torsion. A unique relationship between volume and torsion is therefore ex...

JACINTA BALDWIN,1 RODNEY J. SNOW,2 MICHAEL F. CAREY,3 AND MARK A. FEBBRAIO1 1Exercise Physiology and Metabolism Laboratory, Department of Physiology, The University of Melbourne, Parkville, 3052 Victoria; 2School of Human Movement, Deakin University, Burwood, 3125 Victoria; and 3Exercise Metabolism Unit, Department of Biomedical Sciences, Victoria University of Technology, Footscray, 3011 Victo...

Speth, Robert C., William T. Barry, M. Susan Smith, and Kevin L. Grove. A comparison of brain angiotensin II receptors during lactation and diestrus of the estrous cycle in the rat. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R904–R909, 1999.—During lactation there are many dramatic alterations in the hypothalamic-pituitary (HP) axis, as well as an increased demand for food ...

Stein, Kenneth M., Jeff Walden, Neal Lippman, and Bruce B. Lerman. Ventricular response in atrial fibrillation: random or deterministic? Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H452–H458, 1999.—The ventricular response in atrial fibrillation is often described as ‘‘chaotic,’’ but this has not been demonstrated in the strict mathematical sense. A defining feature of chaotic systems is sen...

GERALDINE CORRIGAN,1 DEEPA RAMASWAMY,1 OSUN KWON,1 F. GRAHAM SOMMER,2 EDWARD J. ALFREY,3 DONALD C. DAFOE,3 RICHARD A. OLSHEN,4 JOHN D. SCANDLING,3 AND BRYAN D. MYERS1 1Department of Medicine, Division of Nephrology, 2Diagnostic Radiology, 3Adult Kidney and Kidney/Pancreas Transplant Program, and 4Division of Biostatistics, Department of Health Research and Policy, Stanford University School of ...

Otsuka, Eri, Akira Yamaguchi, Shigehisa Hirose, and Hiromi Hagiwara. Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid. Am. J. Physiol. 277 (Cell Physiol. 46): C132–C138, 1999.—The stromal cell line ST2, derived from mouse bone marrow, differentiated into osteoblast-like cells in response to ascorbic acid. Ascorbic acid induced alkaline p...

MicroRNAs (miRNA) are short endogenous noncoding RNA molecules that regulate fundamental cellular processes such as cell differentiation, cell proliferation and apoptosis through modulation of gene expression. Critical to understanding the role of miRNAs in this regulation is a method to rapidly and accurately quantitate miRNA gene expression. Existing methods lack sensitivity, specificity and ...