BACKGROUND Niacin induces the release of vasodilating prostaglandins, for which receptors are present within the pulmonary arterial circulation. We hypothesized that immediate-release niacin would reduce right ventricular systolic pressure in patients with pulmonary hypertension in a randomized, double-blinded, single-dose provocation study. METHODS We recruited inpatient subjects with a Dopp...

In para-cycling, competitors are classed based on functional impairment resulting in cyclists with neurological and locomotor impairments competing against each other. In Paralympic competition, classes are combined by using a factoring adjustment to race times to produce the overall medallists. Pacing in short-duration track cycling events is proposed to utilize an "all-out" strategy in able-b...

Application of the conventional X.500 approach to naming has heretofore, in the experience of the authors, proven to be an obstacle to the wide deployment of directory-enabled applications on the Internet. We propose a new directory naming plan that leverages the strengths of the most popular and successful Internet naming schemes for naming objects in a hierarchical directory. This plan can, w...

Abstract Evaluation of the representative cartographic techniques demonstrated that there are still considerable challenges facing methods marine geodetic, geophysical and bathymetric data visualisation. In an oceanic seafloor formation, interaction between geological structural elements topographical relief can be analysed by advanced mapping. present study, a correlation geodesy, geophysics t...

the sscp technique is based on the appearance of new “refolding” conformations during electro-phoresis due to mutation. in order to develop a simple, non-radioactive sscp analysis method so that it can reliably detect single nucleotide changes in pcr products up to 500 bp in length, extensive optimisation trials were performed . the best separation of sscp bands of pcr products up to 500 bp in ...

J. C. Maréchal*, M. P. Sarma, S. Ahmed and P. Lachassagne Indo-French Centre for Groundwater Research, National Geophysical Research Institute, Uppal Road, Hyderabad 500 007, India National Geophysical Research Institute, Uppal Road, Hyderabad 500 007, India Bureau de Recherches Géologiques et Minières–French Geological Survey, Service EAU, Unite RMD, 1039 avenue de Pinville, F-34000 Montpellie...