BACKGROUND We and others have previously demonstrated that adipose-derived stem cells (ASCs) transplantation improve cardiac dysfunction post-myocardium infarction (MI) under hemodynamic stress in rats. The beneficial effects appear to be associated with pleiotropic factors due to a complex interplay between the transplanted ASCs and the microenvironment in the absence of cell transdifferentiat...

orking in a hospital is quite different from sitting in a lecture hall listening to the professor. Having been charmed with the clinical aspects of medicine during ward postings in clinical years, interns enjoy the period of internship to the full extent. Should I be asked for my valued phase in the whole MBBS study – It would undoubtedly be internship for it offered me learning opportunity, be...

The metaphysician, though never so good a theorist, the physician, however sound a practitioner, must both give place to one who, sitting by the well of knowledge, dispenses with grace and justice to his thirsting brethren. He who, by opportunity and industry, can draw the deepest, to him we may look for the best and clearest supply. The pathology of insanity is still in its infancy; nothing is...

The role of locomotion in the acquisition and transfer of spatial knowledge was investigated in 144 five-, seven- and eleven-year-old children. Two experiments were conducted in the Kiel locomotor maze. In the first experiment, one group of children explored the spatial layout by walking through the maze, while another learned the maze by surveying the layout. In the second experiment, children...

Cells have the ability to actively sense their mechanical environment and respond to both substrate stiffness and stretch by altering their adhesion, proliferation, locomotion, morphology, and synthetic profile. In order to elucidate the interrelated effects of different mechanical stimuli on cell phenotype in vitro, we have developed a method for culturing mammalian cells in a two-dimensional ...

The purpose of this study was to ascertain the importance of learning a motor task in a sitting position and its influence on gait. Thirty-one healthy subjects, divided into three groups, were asked to learn a synchronous heel-up-heel-down rhythm task in a sitting position and to reproduce the rhythm during their gait cycle on three separate occasions over a three-day period. This study provide...

Given previous evidence that bodily states can impact basic cognitive processes, we asked whether such impact can also be demonstrated for creative cognition. In particular, we had participants perform a design improvement task and a consequences imagination task while standing up, walking in a predetermined pattern, or walking freely. Results show better divergent-thinking performance with unc...

[Purpose] This study observed the plantar pressure between flexible flatfoot and normal foot on different walking conditions to find out if flexible flatfoot needs the treatment and how the plantar pressure change while walking upstairs and downstairs. [Subjects and Methods] Fifteen adults with mild flexible flatfoot, fifteen adults with severe flexible flatfoot and fifteen adults with normal f...