OBJECTIVE To determine the clinical and EEG findings in children with infantile spasms at their initial presentation to the Neurophysiology Department, Children's Hospital, Lahore, Pakistan. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY The Neurophysiology Department, Children's Hospital, Lahore, Pakistan, from January 2008 to December 2010. METHODOLOGY Children aged < 24 ...

PURPOSE The goal of the study was to assess the outcome of antiepileptic drug (AED) withdrawal in children and adolescents with cryptogenic focal epilepsies (CFE). METHODS Medical records of consecutive patients with CFE from two referral hospitals were retrospectively evaluated over a nine-year period. Inclusion criteria were: (1) diagnosis of CFE according to the ILAE criteria, (2) less tha...

Aim: We aimed to evaluate clinical and laboratory features in children who presented unprovoked seizure for the first time also determine possible risk factors recurrence. Materials Methods: A total of 219 patients (113 female, 106 male) a were included study. Demographic, findings (type duration seizures, recurrence, antiseizure drugs), neuroimaging electroencephalography (EEG) results recorde...

Pachygyria or incomplete lissencephaly is a developmental condition due to abnormal migration of neurons. The association of seizures in this condition warrants investigation like electroencephalogram (EEG) and magnetic resonance imaging (MRI). 18F-flurodeoxyglucose positron emission topography computed topography (18F-FDG PET/CT) has a potential role in commenting of wide...

Neurologists typically study the brain activity through acquired biomarker signals such as Electroencephalograms (EEGs) which have been widely used to capture the interactions between neurons or groups of neurons. Detecting and identifying the abnormal patterns through visual inspection of EEG signals are extremely challenging and require constant attention for well trained and experienced spec...

Is directionality of electroencephalographic (EEG) synchronization abnormal in amnesic mild cognitive impairment (MCI) and Alzheimer's disease (AD)? And, do cerebrovascular and AD lesions represent additive factors in the development of MCI as a putative preclinical stage of AD? Here we reported two studies that tested these hypotheses. EEG data were recorded in normal elderly (Nold), amnesic M...

Unilateral destructive brain lesions of early development can result in compensatory thickening of the ipsilateral cranial vault. The aim of this study was to determine the frequency of these bone changes among patients with epilepsy and precocious destructive lesions, and whether a relationship exists between these changes and epileptiform discharges lateralization. Fifty-one patients had thei...

Objective: To study the importance of EEG and CT scan as a diagnostic aid for accurate diagnosis in various seizure disorders in children from Bhubaneswar,Orissa,India. Design: Cross-sectional. Setting: Urban teritiary care teaching hospital. Method: A total of 52 children with seizure disorder were included; 26 of them were having partial seizures, while the rest (26) were having generalised s...

INTRODUCTION The question as to whether an electroencephalogram (EEG) needs to be carried out as a preliminary study in patients with dementia is currently the subject of some controversy. AIMS Our aim was to determine the value of conventional and quantitative analysis of EEG recordings in the treatment of dementia. PATIENTS AND METHODS The EEG recordings of patients diagnosed with a syndr...

AIM To assess the diagnostic value of amplitude-integrated electroencephalography (EEG) in comparison to standard EEG in newborns without severe hypoxic-ischemic encephalopathy who were at risk for seizures. METHODS The study included a consecutive series of 18 term newborns without severe hypoxic-ischemic encephalopathy, but with clinical signs suspicious of epileptic seizures, history of lo...