The mechanism by which ethosuximide reduces thalamic low-threshold calcium current (LTCC) was analyzed using voltage-clamp techniques in acutely isolated ventrobasal complex neurons from rats and guinea pigs. The ethosuximide-induced reduction of LTCC was voltage dependent: it was most pronounced at more-hyperpolarized potentials and did not affect the time course of activation or inactivation ...

The aim of this study is to analyze the graphic features and the clinical significance of the focal interictal paroxysmal abnormalities (FIPA) which can be found in the EEG of patients with typical absences, on the basis of 29 personal cases. The children (15 female; mean age at the first evaluation=8.2 years, range 4.8-14.3 years) were particularly selected, because they only showed absence se...

PURPOSE Generalized paroxysmal fast activity (GPFA), an EEG pattern with variable frequency and duration, is usually noted in symptomatic/cryptogenic generalized epilepsies. However, GPFA has also been reported in a few patients with genetic generalized epilepsy (GGE) who presented with typical absence seizures (TAS). Our aim was to report the results of long-term follow-up and genetic findings...

Two boys with bilateral agenesis of kidneys and ureters were the product of a consanguineous marriage. This family and previous reports of familial bilateral renal agenesis support the supposition that a minor proportion of cases of BRA is caused by the homozygous state of an autosomal recessive gene.

EEG recording is used in veterinary medicine as a diagnostic tool to support clinical diagnosis of idiopathic epilepsy and to identify focal seizure activity. This retrospective study was designed to compare EEG procedures in 23 dogs with idiopathic epilepsy before and after phenobarbital treatment. Differences among standard deviations for particular bands were significant. During phenobarbita...

The rhythms of spontaneously occurring seizures (spike-wave discharges, SWD) and motor activity, as well as the relationship between SWD and sleep-wake states were investigated in the WAG/Rij rat model of absence epilepsy. In order to establish whether SWD are controlled by external (Zeitgebers) or by endogenous factors such as circadian influences or the state of vigilance, the study was perfo...

congenital absence of left circumflex artery is a rare congenital anomaly of the coronary arteries. the prevalence of the anomaly in different studies ranges from 0.6% to 1.3%. of these, 80% are benign and asymptomatic and 20% are clinically important. we report a 56-year-old man presented with acute resting chest pain who was diagnosed as having acute anterolateral infarction accompanied by el...

Abstract Absence of evidence arguments are indispensable to comparative neurobiology. The absence in a given species homologous neural architecture strongly correlated with type conscious experience humans should be able taken as prima facie reason for concluding that the question does not have capacity experience. reasoning is, however, widely disparaged being both logically illicit and unscie...

a continually absent person is “a person which is almost a long time laps from his absence and there is not any news behalf him” (article 1011 of civil code). the rules and effects of absence of continually absent person which chapter fifth of civil code specified to it, are mostly derived from jurisprudence, and in fact the base of civil code in this part is emamie jurisprudence. absence of ab...