*Corresponding author: Dr. Mohammad Amin Mosleh-Shirazi, Department of Radiotherapy and Oncology, Shiraz University of Medical Sciences, Shiraz, Iran. Fax: +98 711 6474320 E-mail: [email protected] Background: The dose rate distribution delivered by a low dose rate 137Cs pellet source, a spherical source used within the source trains of the Selectron gynecological brachytherapy system, was inv...

RATIONALE Fever control may improve vascular tone and decrease oxygen consumption, but fever may contribute to combat infection. OBJECTIVES To determine whether fever control by external cooling diminishes vasopressor requirements in septic shock. METHODS In a multicenter randomized controlled trial, febrile patients with septic shock requiring vasopressors, mechanical ventilation, and seda...

introduction:  skin  sparing  is  one  of  the  most  desirable  characteristics  of  high  energy  photon  beams. however, the photons emerging from the target of linacs are contaminated by secondary  electrons  as  a  result  of  their  interactions  with  air,  collimators,  flattening  filter  and  any  other  objects in their path. this phenomenon tends to increase the skin dose received b...

introduction: the aim of present study was to estimate effective dose from most common procedures performed in nuclear medicine departments of golestan province. methods: data of nuclear medicine procedures performed in 2 nuclear medicine departments in golestan province were collected during 4 years. effective dose, collective effective dose and effective dose per examination were calculated u...

PURPOSE To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers, and to develop an efficient way to validate the dose delivered for the patients during treatments. MATERIALS AND METHODS A pixel-segmented ionisation chamber device, IMRT MatriXX™ and Multicube™ phantom from IBA were used on ten selected Tomotherapy IMRT/IGRT head and ne...

Meclizine and caffeine combination is used for the treatment of morning sickness. Both compounds are teratogenic and caffeine is known to possess anti-fertility activity also. The present study was undertaken to evaluate the reproductive toxic effect of meclizine and caffeine combination. Three doses were taken for the study; low dose (LD; meclizine 3.7 mg/kg and caffeine 3 mg/kg) was selected ...

In this study we investigate the effect of detector size in the dosimetry of small fields and steep dose gradients with a particular emphasis on IMRT measurements. Comparisons of calculated and measured cross-profiles and absolute dose values of IMRT treatment plans are presented. As a consequence of the finite size of the detector that was used for the commissioning of the IMRT tool, local dis...

The pharmacokinetics of marbofloxacin in pigs were evaluated as a function of dose and animal age following intravenous and intramuscular administration of a 16% solution (Forcyl(®) ). The absolute bioavailability of marbofloxacin as well as the dose proportionality was evaluated in 27-week-old fattening pigs. Blood PK and urinary excretion of marbofloxacin were evaluated after a single intramu...

PURPOSE The purpose of this study was to compare two inverse planning algorithms for cervical cancer brachytherapy and a conventional manual treatment planning according to the MUW (Medical University of Vienna) protocol. MATERIAL AND METHODS For 20 patients, manually optimized, and, inversely optimized treatment plans with Hybrid Inverse treatment Planning and Optimization (HIPO) and with In...