Abstract Taste as an eating quality factor of beef can be influenced by the selection raw material and aging method. The metabolic changes different breeds during were analyzed in wet-aged dry-aged up to 28 days using samples from M. longissimus thoracis et lumborum Simmental Black-and-White 1 H NMR spectroscopy. Breed affected metabolome before beef. concentration 24 30 metabolites differed si...

BACKGROUND Anaemia is a common complication associated with haemodialysis and is usually managed by treatment with recombinant human erythropoietin (rHuEPO). However, many patients remain hyporesponsive to rHuEPO treatment despite adequate iron therapy. The effect of L-carnitine administration on rHuEPO dose and/or haematocrit in haemodialysis patients has been previously reported with equivoca...

BACKGROUND This study examined whether carnitine deficiency is a risk factor and should be viewed as a mechanism during the development of gentamicin (GM)-induced ARF as well as exploring if carnitine supplementation could offer protection against this toxicity. METHODS Adult male Wistar albino rats were assigned to one of six treatment groups: group 1 (control) rats were given daily intraper...

Maternofetal transport of l-carnitine, a molecule that shuttles long-chain fatty acids to the mitochondria for oxidation, is thought to be important in preparing the fetus for its lipid-rich postnatal milk diet. Using brush-border membrane (BBM) vesicles from human term placentas, we showed that l-carnitine uptake was sodium and temperature dependent, showed high affinity for carnitine (apparen...

PURPOSE Previously we demonstrated expression and localization of carnitine/organic cation transporters, OCTN1 and OCTN2, in human corneal and conjunctival epithelia. The present study aimed to examine the characteristics of L-carnitine transporters in cultured human limbal corneal (HCLE) and conjunctival epithelial (HCjE) cells. METHODS Time-course, Na(+)-dependence, kinetics, energy- and pH...

FRITZ, IRVING B., AND KENNETH T. N. YUE. Ejects of carnitine on acetyl-CoA oxidation by heart muscle mitochondria. Am. J. Physiol. 206(3) ~~31-535. 1964.~Acetyl-I-C14-CoA was oxidized by heart muscle mitochondria incubated in the absence of ATP and carnitine at a rate approximately $ioo that at which acetic acid-r -Cl4 was converted to CO2 in the presence of ATP. Carnitine addition increased th...