History A 37-year-old man first presented in September, 1997 with scaly plaques on the lower limbs, clinically consistent with plaque psoriasis. He was known to be hepatitis B surface antigen positive and hepatitis B e antigen negative. The psoriasis was subsequently treated with topical steroid and acitretin for ten weeks with a good response. He then defaulted follow-up, but reattended in Apr...

836 © 2007 The Authors JEADV 2007, 21, 822–849 Journal compilation © 2007 European Academy of Dermatology and Venereology 5 Hesse S, Berbis P, Privat Y. Keratoderma palmoplantaris papulosa (Bushcke–Fischer’s disease): efficacy of acitretin. Br J Dermatol 1993; 128: 104–105. 6 Horikoshi M, Kuroda K, Tajima S. Puncate palmoplantar keratoderma with pigmentary lesions on the dorsa of feet and ankle...

Blastomycosis-like pyoderma is a rare, vegetating skin lesion that is an unusual exaggerated tissue reaction possibly to prolonged primary or secondary bacterial infection. We report a case of blastomycosis-like pyoderma in a man with Down syndrome, diabetes mellitus and hypothyroidism who responsed poorly to conventional therapies, including antibiotics and correction of predisposing factors f...

GEKG: generalized eruptive keratoacanthoma of Grzybowski KA: keratoacanthoma PDT: photodynamic therapy INTRODUCTION Generalized eruptive keratoacanthoma of Grzybowski (GEKG), a rare variant of keratoacanthoma (KA), affects widespread areas of the skin and mucous membranes. First described in 1950, this condition is exceptionally difficult to treat. Systemic retinoids or cyclophosphamide, althou...