نتایج جستجو برای: acting antiviral

تعداد نتایج: 108524  

2015
Meike Dittmann Hans-Heinrich Hoffmann Margaret A. Scull Rachel H. Gilmore Kierstin L. Bell Michael Ciancanelli Sam J. Wilson Stefania Crotta Yingpu Yu Brenna Flatley Jing W. Xiao Jean-Laurent Casanova Andreas Wack Paul D. Bieniasz Charles M. Rice

Interferon-stimulated genes (ISGs) act in concert to provide a tight barrier against viruses. Recent studies have shed light on the contribution of individual ISG effectors to the antiviral state, but most have examined those acting on early, intracellular stages of the viral life cycle. Here, we applied an image-based screen to identify ISGs inhibiting late stages of influenza A virus (IAV) in...

Journal: :Journal of virology 1983
H Arnheiter O Haller

The allele Mx regulates the extent to which interferon alpha/beta inhibits the growth of influenza viruses in mouse cells such as peritoneal macrophages. The time course of induction of the antiviral state against an influenza A virus is comparable in macrophages with and without Mx and is similar to that found with vesicular stomatitis virus. In contrast, the decay of the antiviral state again...

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