Helicobacter Pylori (HP) were found in 878 (73%) of 1205 patients undergoing upper G-I endoscopy with multiple biopsies for gastroduodenal diseases. HP were present in similar percentages among patients with active (89%) or healed (81%) peptic ulcer as well as in non ulcerous dyspeptics affected with gastritis (85%). 96% of active chronic gastritis were infected by HP as compared with 55% of qu...

A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR). All the synthesized compounds were evaluated for their in vivo anti ulcerogenic activity using Albino rats (weighing 180-220 g). The interactions between the compounds and active site residues of H+/K+ ATPase were investigated b...

BACKGROUND Helicobacter pylori affects gastric epithelium integrity by acceleration of apoptosis. However, it remains unclear what product of the bacteria causes apoptosis, or whether or not the apoptosis is involved in the development of ulcers. AIMS To elucidate the factor from H pylori that causes acceleration of apoptosis and the role of apoptosis in the development of duodenal ulcer in H...

A 54-year-old man visited our emergency department with severe upper abdominal pain. Physical examination revealed muscle guarding and rebound tenderness. Emergent sonography revealed marked thickening of the duodenal wall and a linear hyperechoic band involving the entire wall of the duodenal bulb (Figure 1, arrow). Small hyperechoic spots were found continuously moving from the band towards t...

OBJECTIVE To compare the outcome and cost of care for leg ulcers in community leg ulcer clinics in Stockport District Health authority with Trafford District Health Authority as a control. DESIGN Detailed cost and efficacy studies conducted prospectively over a three month period in both districts both before and one year after the introduction of five leg ulcer clinics in Stockport. SETTIN...

The association ofHelicobacter pyloriwith peptic ulcer disease and gastric cancer was first proposed by Warren and Marshall in 1983 (Warren and Marshall, 1983). In February 1994, the National Institutes of Health Consensus Development Conference concluded thatH. pylori infection is themajor cause of peptic ulcer disease, and all patients with confirmed peptic ulcer disease associatedwithH. pylo...

OBJECTIVES To show important aspects of gastroduodenal peptic ulcer and of Helicobacter pylori infection in children and adolescents. SOURCES Technical textbooks and MEDLINE and LILACS databases including publications between 1966 and 2006. SUMMARY OF THE FINDINGS The etiology of peptic ulcer in children and adolescents may be primary, associated with H. pylori infection, or secondary, in w...

Introduction: The goal of the study was to assess knowledge and management Buruli ulcer disease in Sekyere Afram Plains District Ashanti Region.
 Methods: used a quantitative type cross-sectional design with sample size 251 comprising Ulcer (BU) patients, health workers community members as population. structured questionnaire for primary data. because respondents were literates could read...

QUESTION UNDER STUDY Repetitive skin trauma and reduced pressure pain sensation are necessary components of plantar ulcer risk in patients with diabetic neuropathy. The diagnostic value of measuring pressure nociception to detect ulcer risk is, however, unknown. Instead, measuring the vibration perception threshold (VPT) by 64 Hz graduated Rydel-Seiffer tuning fork has become standard clinical ...

The aim of this study was to characterize gastric myoelectrical activity in patients with recurrent gastric ulcer (GU) or duodenal ulcer (DU), and to compare gastric motility between these two groups of patients. Studies were performed in 59 patients with recurrent active peptic-ulcer disease as diagnosed by gastrointestinal endoscopy: 31 patients had a GU and 28 patients had a DU. Gastric myoe...