BACKGROUND The association of human leukocyte antigen B27 (HLA-B27) with anterior uveitis is well known. The prevalence of HLA-B27 and its relation to anterior uveitis is related to race and geographic location. The association is strongest in Western countries and weakest in Eastern countries. Data regarding this association from Middle Eastern countries are limited. Thus, we undertook the stu...

BACKGROUND Uveitis is an autoimmune disease of the eye that refers to any of a number of intraocular inflammatory conditions. Because it is a rare disease, uveitis is often overlooked, and the possible associations between uveitis and extra-ocular disease manifestations are not well known. The aim of this study was to characterize uveitis in a large sample of patients and to evaluate the relati...

BACKGROUND Anterior uveitis is the most common extra-articular manifestation of ankylosing spondylitis (AS). AS-related anterior uveitis frequently presents as acute, recurrent iridocyclitis; therefore, AS is often initially suspected by an ophthalmologist, not by a rheumatologist. In this study, we aimed to investigate the relationship between the recurrence of anterior uveitis and the subsequ...

BACKGROUND The objectives of this study are to assess Canadian ophthalmologists' awareness of established uveitis treatment guidelines and clinical management of uveitis and to assess the frequency of government applications for immunomodulatory therapy (IMT) and identify primary prescribers. A 25-item questionnaire was sent to 759 practicing Canadian ophthalmologists. Six questions assessed de...

PURPOSE Transforming growth factor-beta2 is known to be present at elevated levels in the aqueous humor of patients with primary open angle glaucoma (POAG) and diabetes but not in uveitis-related secondary glaucoma. We investigated total TGF-beta2 levels and levels of the active form of TGF-beta2 in the aqueous humor of eyes with different types of glaucoma. METHODS The concentration of the t...

Cellular retinaldehyde binding protein (CRALBP) is an autoantigen in spontaneous equine recurrent uveitis. In order to test whether CRALBP contributes to human autoimmune uveitis, the specificity of antibodies from human uveitis patient's sera was first evaluated in two-dimensional (2D) Western blot analysis. Subsequent identification of the immunoreactive proteins by mass spectrometry resulted...

AIM To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. MATERIALS AND METHODS The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease...

OBJECTIVE This study aimed to describe the clinical characteristics of uveitis presenting de novo in the elderly. DESIGN The study design was a description of a retrospectively identified case series. PARTICIPANTS A population of 138 patients (209 eyes) with uveitis beginning after age 60 was analyzed. RESULTS Uveitis in the elderly accounted for 10.4% of the authors' uveitis population. ...

PURPOSE To identify any patterns in the cause of anterior uveitis in a Turkish population and compare them with results from previous studies. METHODS The clinical records of 75 patients between January 2009 and January 2010 were retrospectively analyzed and classified as anterior uveitis according to Standardization of Uveitis Nomenclature criteria. Complete blood count, sedimentation rate, ...

Uveitis a vision threatening inflammation of uvea is prevalent worldwide. In the United States uveitis has prevalence of 2.3 million people and causes 10% of all cases of blindness. Uveitis is classified by the ocular structures involved e.g., anterior, intermediate, posterior and panuveitis.0cular TB(Eales’ disease) is common in patients from Indian sub-continent. Frequent uveitis etiologies i...