نتایج جستجو برای: acute myeloid leukaemia
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Haematological disorders are getting more and more molecularly defined. This is specially so in the field of haematological malignancies. The molecular understanding has helped in fine-tuning the diagnosis, prognosis and management. The tests are becoming widely available and they enjoy both sensitivity and specificity. Following is an overview of clinical applications of molecular haematology,...
Acute myeloid leukaemia (AML) is a blood cancer affecting cells of myeloid lineage. It is characterised by rapid growth of malignant leukocytes that accumulate in the bone marrow and suppress normal haematopoiesis. This systemic disease remains a serious medical burden worldwide. Characterisation of protein antigens specifically expressed by malignant cells, but not by healthy leukocytes, is vi...
1. Kantarjian H, Ravandi F, O’Brien S, et al. Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia. Blood. 2010;116(22):4422-4429. 2. Juliusson G, Antunovic P, Derolf A, et al. Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry. Blood. 2009;113(18):4179-4187. 3. Jul...
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