Urinary indices are classically believed to allow differentiation of transient (or pre-renal) acute kidney injury (AKI) from persistent (or acute tubular necrosis) AKI. However, the data validating urinalysis in critically ill patients are weak. In the previous issue of Critical Care, Pons and colleagues demonstrate in a multicenter observational study that sodium and urea excretion fractions a...

We report a case of a heretofore healthy 18-year-old man who presented with a 2-day history of nausea, vomiting and stomach ache while taking creatine monohydrate for bodybuilding purposes. The patient had acute renal failure, and a renal biopsy was performed to determine the cause of increased creatinine and proteinuria. The biopsy showed acute tubular necrosis. In the literature, creatine mon...

Submit Manuscript | http://medcraveonline.com Abbreviations: CIN: Contrast-Induced Nephropathy; CIAKI: Contrast-Induced AKI; CKD: Chronic Kidney Disease; Cr: Creatinine; GFR: Glomerular Filtration Ratio; NSF: Nephrogenic Systemic Fibrosis; AMI: ACUTE Myocardial Infarction; NSAIDs: Nonsteroidal Anti-Inflammatory Drugs; AKI: Acute Kidney Injury; ATN: Acute Tubular Necrosis; TIN: Tubulointerstitia...

the specificity of gentamicin for vitamin e deficiency-associated oxidative stresses in the renal proximal convoluted tubules is apparently related to its ability to increasingly facilitate generation of radical species in mitochondria. to determine the ways in which vitamin e manage the currently processes, we conducted a prospective study aimed to investigate the tubular preserving effect of ...

Twelve patients with otherwise uncomplicated acute viral hepatitis (two were HBsAg-positive) developed renal failure. Apart from dehydration due to repeated vomiting in one patient, no factor responsible for precipitating renal failure could be identified. The clinical course was characterised by renal failure with plasma urea concentrations reaching maximum values of 26-69 mmol/l (175-416 mg/1...

Submit Manuscript | http://medcraveonline.com Abbreviations: CIN: Contrast-Induced Nephropathy; CIAKI: Contrast-Induced AKI; CKD: Chronic Kidney Disease; Cr: Creatinine; GFR: Glomerular Filtration Ratio; NSF: Nephrogenic Systemic Fibrosis; AMI: ACUTE Myocardial Infarction; NSAIDs: Nonsteroidal Anti-Inflammatory Drugs; AKI: Acute Kidney Injury; ATN: Acute Tubular Necrosis; TIN: Tubulointerstitia...

Thinners are mixtures of organic solvents commonly containing toluene, xylene, acetone, hexane, benzene and methyl isobutyl ketone. This report describes a case of rhabdomyolysis with acute tubular necrosis and renal failure, most likely attributable to toluene, following occupational exposure to thinners while cleaning a steel water tank. These adverse health effects have previously been repor...