نتایج جستجو برای: acylhomoserine lactone

تعداد نتایج: 4758  

Journal: :Journal of bacteriology 2004
E Valade F M Thibault Y P Gauthier M Palencia M Y Popoff D R Vidal

Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infection of humans and animals. The virulence of this pathogen is thought to depend on a number of secreted proteins, including the MprA metalloprotease. We observed that MprA is produced upon entry into the stationary phase, when the cell density is high, and this prompted us to study cell density-dependent regula...

2011
Live L Nesse Kristin Berg Lene K Vestby Ingrid Olsaker Berit Djønne

BACKGROUND In Gram-negative bacteria, the most commonly studied quorum sensing signals are the N-acylhomoserine lactones (AHLs). In Salmonella, AHLs are recognized by SdiA, which is believed to be a sensor of AHLs produced by other bacteria, since Salmonella does not produce AHLs itself. It has been speculated that AHLs produced by the gastrointestinal flora may influence the regulation of viru...

Journal: :Chembiochem : a European journal of chemical biology 2009
Verena Thiel Brigitte Kunze Pankaj Verma Irene Wagner-Döbler Stefan Schulz

N-Acylhomoserine lactones (AHLs) are used by a wide variety of bacteria for cell-cell communication in "quorum-sensing". These compounds are derived from L-homoserine lactone and a fatty acid, which varies in chain-length, degree of saturation, and the presence or absence of an oxygen atom at C-3. In this study we describe for the first time the occurrence of acyl chains carrying a methyl branc...

2016
Janak Raj Joshi Netaly Khazanov Hanoch Senderowitz Saul Burdman Alexander Lipsky Iris Yedidia

Quorum sensing (QS) is a population density-dependent regulatory system in bacteria that couples gene expression to cell density through accumulation of diffusible signaling molecules. Pectobacteria are causal agents of soft rot disease in a range of economically important crops. They rely on QS to coordinate their main virulence factor, production of plant cell wall degrading enzymes (PCWDEs)....

2011
Patrick Bijtenhoorn Hubert Mayerhofer Jochen Müller-Dieckmann Christian Utpatel Christina Schipper Claudia Hornung Matthias Szesny Stephanie Grond Andrea Thürmer Elzbieta Brzuszkiewicz Rolf Daniel Katja Dierking Hinrich Schulenburg Wolfgang R. Streit

In Pseudomonas aeruginosa, the expression of a number of virulence factors, as well as biofilm formation, are controlled by quorum sensing (QS). N-Acylhomoserine lactones (AHLs) are an important class of signaling molecules involved in bacterial QS and in many pathogenic bacteria infection and host colonization are AHL-dependent. The AHL signaling molecules are subject to inactivation mainly by...

2014
Wen-Si Tan Nina Yusrina Muhamad Yunos Pui-Wan Tan Nur Izzati Mohamad Tan-Guan-Sheng Adrian Wai-Fong Yin Kok-Gan Chan

N-acylhomoserine lactones (AHL) plays roles as signal molecules in quorum sensing (QS) in most Gram-negative bacteria. QS regulates various physiological activities in relation with population density and concentration of signal molecules. With the aim of isolating marine water-borne bacteria that possess QS properties, we report here the preliminary screening of marine bacteria for AHL product...

2017
Rong Chen Ruichen Lv Lisheng Xiao Min Wang Zongmin Du Yafang Tan Yujun Cui Yanfeng Yan Yanping Luo Ruifu Yang Yajun Song

Two-component systems in Acinetobacter baumannii are associated with its virulence, drug resistance, motility, biofilm formation, and other characteristics. In this study, we used RecAb , a genetic engineering method, to investigate the function of A1S_2811 in A. baumannii strain ATCC17978. A1S_2811, a hypothetical hybrid sensor histidine kinase/response regulator, has four histidine-containing...

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