Alzheimer’s disease (AD) is the most popular type of dementia in elderly and is described by a progressive loss of cognitive capacity and severe neurodegeneration which typically begins with memory deficits. The major biomarkers of AD include total tau, phosphorylated-tau and 42 amino acid isoform of amyloid beta that reflect neurodegeneration and indicate the pathophysiological processes in AD...

Alzheimer disease (AD), the most common cause of dementia, is an irreversible progressive neurodegenerative condition. It is characterized by the salient inflammatory features, microglial activation and increased levels of pro-inflammatory cytokines which contribute to the inflammatory states of the CNS. Accumulating data suggest the key role of inflammation in AD pathogenesis. In a prospective...

the intelligent transportation system (its) provides wireless and mobile communication between vehicles and infrastructure to improve the safety of transportation and make the journey more enjoyable. this system consists of many fixed and mobile nodes (vehicles, trains, vessels, air planes), wireless and wired telecommunication technologies to exchange information between mobile nodes or betwee...

the role of transforming growth factor (tgf)-β1, interferon (ifn)-γ, interleukin (il)-2, il-3, and il-6 in the pathogenesis of alzheimer's disease (ad) has long been reported in literature. in this case-control study, the concentrations of these cytokines in altered t lymphocytes, as well as serum vitamin b12, have been compared in terms of factors such as, age, the clinical course and the pati...