This paper describes a hardware to support distributed associative memories, in particular the ADAM neural network architecture. The system is designed to support a large number of moderately sized ADAM memories on a distributed memory MIMD architecture. The system addresses the issues of weight paging to allow neural networks of very large size to be executed using only a relatively small phys...

ADAM-17 is a matrix metalloproteinase-like enzyme involved in the release of several ligands that have been shown to promote both cancer formation and progression. These ligands include transforming growth factor-alpha, amphiregulin, heparin-binding epidermal growth factor, epiregulin and tumor necrosis factor-alpha. In this investigation, we measured the expression of total ADAM-17 by enzyme-l...

A natural extension of the trend of increased involvement in science is the concept of a Robot Scientist [King et al. (2004),King et al. (2009)]. A Robot Scientist automatically: originates hypotheses to explain observations, devises experiments to test these hypotheses, physically runs the experiments using laboratory robotics, interprets the results to change the probability of hypotheses, an...

......................................................................................................................... 2 Trust: Economic Notions and its role in Money and Banking – An Introduction ....... 11 Realism .................................................................................................................... 12 Open Systems and Closed systems .............................

The presence of moral evil (sin) in the world is relatively easy for the Christian creationist to explain, and free choice is key to that explanation. To Christian evolutionist and professor of biology Daniel Brannan, the idea of a very good Creation and an Adam and Eve who were deceived and sinned is not only incoherent but also makes God the cause of sin. Brannan proposed that Christians acce...

REGULATION OF NUCLEAR LAMIN POLYMERIZATION BY IMPORTIN  Adam, Stephen A., Kaushik Sengupta, and Robert D. Goldman From Department of Cell and Molecular Biology Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 1 These authors contributed equally to this work. Address correspondence to Stephen A. Adam, Ph.D., W129 303 E. Chicago Avenue, Chicago IL 60611 Fax: 312-503-7...

The ADAMs are a family of membrane proteins possessing a disintegrin and metalloprotease domain. One of their main functions is shedding of membrane proteins. The aim of this study was to test the hypothesis that ADAM-17 (also known as tumor necrosis factor-alpha converting enzyme) is involved in breast cancer progression. Overexpression of ADAM-17 in MCF-7 breast cancer cells increased in vitr...

BACKGROUND Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate to form parts of the peripheral nervous system, muscles, cartilage, and bones of the face. Neural crest-cell migration involves the loss of adhesion from the surrounding neuroepithelium and a corresponding increase in cell adhesion to the extracellular matrix (ECM) present in ...