Materials and methods this was a cross-sectional study of 36 outpatients, aged 20-75 yrs., with MetS whose diagnosis was established based on the International Diabetes Federation criteria and hypopituitarism, in the presence or after pituitary adenoma treatment. In the anthropometric assessment the body weight, height, body mass index (BMI) and waist circumference (WC) were measured. Furthermo...

purpose: to study early treatment outcomes and complications of gamma knife radiosurgery (gkrs) in patients with functional and nonfunctional adenomas. methods: one hundred patients with a pituitary adenoma who were treated between 2011 and 2014 at iran gamma knife center were studied. the patients were followed up at least 2 years. radiosurgery was performed using the leksell gamma unit. the m...

an ectopically placed parathyroid in the mediastinum is a rare cause of persistent or recurrent primary hyperparathyroidism. they are rarely in a huge size. we report a case of a 70-year-old man with a history of total parathyroidectomy and thymectomy presented with a lack of appetite, nausea, and generalized bone pain, polydipsia and a calcium level of 14.4 mg/dl. 99m tc-sestamibi scintigraphy...

Leptin, the obese (ob) gene product, is an adipocyte-derived satiety factor that is involved in the regulation of food ingestion and body weight. To investigate glucocorticoid regulation of leptin synthesis and secretion in humans, we measured plasma leptin levels in patients with Cushing's syndrome with adrenal or pituitary adenoma and in patients with iatrogenic Cushing's syndrome. Plasma lep...

An 81-year-old female consulted a local physician due to diarrhea. Since general fatigue and body weight loss were observed, she was admitted for detailed examination and treatment. Colonoscopy revealed a circumferential giant tumor with a maximum diameter of 10 cm in the rectum, and biopsy findings indicated villous adenoma. The tumor secreted a large amount of mucus, and a diagnosis of electr...

Obesity has been associated with an increased risk of colorectal neoplasia, but the mechanisms of this potential association have not been elucidated. We hypothesized that the adipokines adiponectin, leptin, and tumor necrosis factor-alpha (TNF-alpha) may mediate an association between obesity and colorectal cancer. We measured plasma concentrations of total and high-molecular-weight (HMW) adip...

While TSH-producing adenoma (TSHoma) is rare, the diagnosis is often delayed because the clinical features are heterogeneous. The patient was a 69-year-old woman who had been referred to the Yachiyo Medical Center in August 2008, because of dyspnea, loss of appetite, weight loss of 10 kg, and diarrhea that lasted 4 years. We diagnosed this patient with pituitary TSH-producing macroadenoma. Thyr...

Metformin and insulin differently affect the risk of colon cancer in type 2 diabetic patients, however their effects on colon adenoma is not clear. PubMed, ISI, Scopus and Cochrane databases were searched for studies reporting. The outcomes were total adenoma; advanced adenoma and recurrent adenoma. Traditional and Bayesian meta-analysis were conducted via random-effects models. Odds ratios (OR...

a rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. the patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. the lesion was not painful and caused asymmetry and mild exophthalmos. microscopic examination revealed that the tumor was composed of two components partly of ...