To the Editor: We commend the excellent work by Jacobson et al. on behalf of the South African Society of Thrombosis and Haemostasis in producing a very necessary set of local guidelines on the management of venous thromboembolism (VTE).1 VTE is a major cause of morbidity and mortality, as highlighted recently by the United States Surgeon General.2 One important nuance worth noting, however, is...

BACKGROUND Pulmonary rehabilitation has become a standard of care for patients with chronic lung diseases. This document provides a systematic, evidence-based review of the pulmonary rehabilitation literature that updates the 1997 guidelines published by the American College of Chest Physicians (ACCP) and the American Association of Cardiovascular and Pulmonary Rehabilitation. METHODS The gui...

INTRODUCTION There is considerable controversy regarding the best method to prevent venous thromboembolism. In 2008, the American College of Chest Physicians (ACCP) published specific guidelines recommending the use of ow-molecular-weight heparin or warfarin, and a target international normalised ratio of 2.0-3.0 for a duration of at least 7-10 days, after elective knee arthroplasties. Many ort...

Abstract Pharmacoeconomics and outcomes research (PEOR) demonstrates the added value of health services and treatments and is used by a variety of individuals in numerous settings to optimize patient care. Currently, 51 PEOR fellowship programs are publicized on Web sites from organizations such as the American College of Clinical Pharmacy (ACCP), the International Society of Pharmacoeconomics ...

The social enterprise concept, a business with specific objectives, has been questioned by scholars and practitioners for its sustainability. More importantly, paucity of research exists on how can be sustainable, indicating the necessity developing sustainable model enterprise, particularly in Asian context. Filling gap literature, present study’s prime objective is to explore model. bodies kn...

INTRODUCTION High levels of the oncoprotein survivin may be detected in the majority of patients with early rheumatoid arthritis (RA). Survivin is a sensitive predictor of joint damage and persistent disease activity. Survivin-positive patients are often poor responders to antirheumatic and biological treatment. The aim of this study was to investigate the reproducibility of survivin status and...

BACKGROUND Information about the variation in the risk for venous thromboembolism (VTE) and in prophylaxis practices around the world is scarce. The ENDORSE (Epidemiologic International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting) study is a multinational cross-sectional survey designed to assess the prevalence of VTE risk in the acut...

This chapter about the use of antithrombotic agents during pregnancy is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that individual patients' values may lead to different choices (for a full understand...

Abbreviations: AASM American Academy of Sleep Medicine; ACCP American College of Chest Physicians; AHI apnea-hypopnea index; AHRQ Agency for Healthcare Research and Quality; ATS American Thoracic Society; CPAP continuous positive airway pressure; EMG electromyogram; ERC Evidence Review Committee; LR likelihood ratio; RDI respiratory disturbance index; REM rapid eye movement; ROC receiver operat...

A lthough clinical practice guidelines offer considerable promise for improving health-care outcomes, significant hurdles exist in implementing guideline recommendations. The conference attendees and invited experts participated in three discussion groups that developed recommendations for assisting the American College of Chest Physicians (ACCP) in adopting strategies for guideline implementat...