Background—In patients with severe aortic stenosis who cannot have surgery, transcatheter aortic valve replacement (TAVR) has been shown to improve survival and quality of life compared with standard therapy, but the costs and cost-effectiveness of this strategy are not yet known. Methods and Results—The PARTNER trial randomized patients with symptomatic, severe aortic stenosis who were not can...

An ideal population health outcome metric should reflect a population's dynamic state of physical, mental, and social well-being. Positive health outcomes include being alive; functioning well mentally, physically, and socially; and having a sense of well-being. Negative outcomes include death, loss of function, and lack of well-being. In contrast to these health outcomes, diseases and injuries...

BACKGROUND Although radical resection and postoperative chemoradiation have been the standard therapy for patients with rectal cancer, preoperative staging by local imaging and chemoradiation are widely used. We used a decision analysis to compare the two strategies for rectal cancer management. METHODS We developed a decision model to compare survival outcomes after postoperative chemoradiat...

BACKGROUND Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measu...

background and purpose: mortality statistics and rates show the development of a country in the world. these statistics are very important for determining the distribution of risk factors of mortality (in age and gender groups, ethnicity and so on) and they are useful for improving health and preventing from important diseases in future planning of countries in societies. materials and methods:...

The number of scholars following the tempo approach in fertility continues to grow, whereas tempo-adjustment in mortality generally still is rejected. This rejection is irrational in principle, as the basic idea behind the tempo approach is independent of the kind of demographic event. Providing the first empirical application to a substantial problem, this chapter shows that mortality tempo-ad...

In this paper, we study the relation between life expectancy and both average income and measures of income inequality in 1980 and 1990, using the 17 Spanish regions as units of analysis. Average income was measured as average total income per household. The indicators of income inequality used were three measures of relative poverty-the percentage of households with total income less than 25%,...

BACKGROUND The increased use of medical therapies has led to increased medical costs. To provide insight into the value of this increased spending, we compared gains in life expectancy with the increased costs of care from 1960 through 2000. METHODS We estimated life expectancy in 1960, 1970, 1980, 1990, and 2000 for four age groups. To control for the influence of nonmedical factors on survi...