INTRODUCTION AND OBJECTIVES Treatment with ferric carboxymaltose improves symptoms, functional capacity, and quality of life in patients with chronic heart failure and iron deficiency. The aim of this study was to assess the cost-effectiveness of ferric carboxymaltose treatment vs no treatment in these patients. METHODS We used an economic model based on the Spanish National Health System, wi...

We write in response to a recent discussion Value Health over the preference weights for EQ-5D-5L.1Norman R. Olsen J. Competing views on EQ-5D-5L valuation set.Value Health. 2020; 23: 574-575Abstract Full Text PDF PubMed Scopus (4) Google Scholar It would appear that there is disagreement and options open move from EQ-5D-3L value framework support reference case lifetime models NICE assessment....

Assays monitoring P2Y12 platelet reactivity can accurately predict which patients will have a poor response to clopidogrel. We sought to determine the cost-effectiveness of using platelet reactivity assays (PRAs) to select a dual-antiplatelet regimen for patients with acute coronary syndrome. A hybrid decision tree Markov model was developed to determine the cost-effectiveness of universal clop...

BACKGROUND High-grade gliomas are aggressive, incurable tumors characterized by extensive diffuse invasion of the normal brain parenchyma. Novel therapies at best prolong survival; their costs are formidable and benefit is marginal. Economic restrictions thus require knowledge of the cost-effectiveness of treatments. Here, we show the cost-effectiveness of enhanced resections in malignant gliom...

OBJECTIVES To investigate the long-term clinical and economic outcomes associated with exenatide versus insulin glargine as "add-on" treatments to oral therapy in individuals with Type 2 diabetes inadequately controlled with combination oral agents in the Swiss setting. METHODS A computer simulation model of diabetes was used to project complications, life expectancy, quality-adjusted life ex...

background: chronic infection with hepatitis c virus (hcv) is increasingly recognized as a major global health problem. illicit injection drug use is an important risk factor for the rising hepatitis c virus (hcv) prevalence in ir iran. objectives: the objective of this study was to determine the long-term effectiveness (total quality adjusted life years (qalys) gained) of methadone maintenance...