نتایج جستجو برای: adjuvants
تعداد نتایج: 6001 فیلتر نتایج به سال:
Vaccines are the most effective agents to control infections. In addition to the pathogen antigens, vaccines contain adjuvants that are used to enhance protective immune responses. However, the molecular mechanism of action of most adjuvants is ill-known, and a better understanding of adjuvanticity is needed to develop improved adjuvants based on molecular targets that further enhance vaccine e...
Shepel, Michael (U.S. Army Biological Laboratories, Fort Detrick, Frederick, Md.) and Maxwell R. Klugerman. Effect of adjuvants on antibody response of rabbits inoculated with Venezuelan equine encephalomyelitis virus. J. Bacteriol. 85:1150-1155. 1963.-Hemagglutination-inhibition, neutralization, and complement-fixation tests were performed on sera of rabbits inoculated with Venezuelan equine e...
The need for new classes of antibacterials is genuine in light the dearth clinical options treatment bacterial infections. prodigious discoveries antibiotics during 1940s to 1970s, a period wistfully referred as Golden Age Antibiotics, have not kept up face emergence resistant bacteria past few decades. There has been renewed interest old drugs, repurposing existing and pairing synergistic or a...
Airway inflammation is the most characterized pathological feature in asthma. The antiinflammatory effect of the adjuvants is reported. Therefore, the effect of two different natural adjuvants on white blood cells (WBC) of lung lavage of sensitized guinea pigs were examined. White blood cells count and differential WBC of lung lavage were examined in control and 3 groups of guinea pigs includin...
Oil-in-water emulsions are potent human adjuvants used for effective pandemic influenza vaccines; however, their mechanism of action is still unknown. By combining microarray and immunofluorescence analysis, we monitored the effects of the adjuvants MF59 oil-in-water emulsion, CpG, and alum in the mouse muscle. MF59 induced a time-dependent change in the expression of 891 genes, whereas CpG and...
Adjuvants are widely used to enhance the effects of vaccines against pathogen infections. Interestingly, different adjuvants and vaccination routes usually induce dissimilar immune responses, and can even have completely opposite effects. The mechanism remains unclear. In this study, urease B subunit (UreB), an antigen of Helicobacter pylori (H. pylori) that can induce protective immune respons...
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