Skin adnexal tumors develop as a consequence of germline pathogenic variants in the cylindomatosis(CYLD) gene patients with Brooke-Spiegler syndrome (BSS), clinical variant CYLD cutaneous syndrome. The first typically present at puberty and they progressively accumulate through adulthood. To improve understanding development skin tumors, we performed here genome-wide methylation analysis on blo...

<p>Nodular hidradenoma (NH) is an uncommon benign skin adnexal tumor that presents usually as solitary intradermal nodule. This study aims to discuss the various clinicopathological features of NH it mimics other tumors, malignancies or metastasis particularly in sites. Twenty-four cases histo-pathologically diagnosed during period from 2016 2021were taken up for study. Their clinical, gr...

A 61-year-old woman was diagnosed with rectal carcinoma. Colectomy and bilateral oophorectomy were performed. There was no peritoneal dissemination. Our case showed that colonic carcinoma coexisted with benign adnexal neoplasm. This fact suggests that the histogenesis of multiple benign or malignant tumors is likely to be secondary to an unexplained stimulus. Perhaps, the collection of cases wi...

bronchiolo-alveolar carcinoma with subcutaneous chest wall metastasis is a very rare presentation. a case of 36- year-old male with metastatic subcutaneous chest nodule of bronchiolo-alveolar carcinoma, diagnosed by fine needle aspiration cytology, is reported here. cutaneous metastases are of diagnostic importance because they may be the first manifestation of an undiscovered internal malignan...

introduction : brooke-spiegler syndrome (bss) is a rare autosomal dominant disease characterized by the development of multiple adnexal cutaneous tumors such as cylindromas, trichoepitheliomas and spiradenomas. case description: a 49 years old female patient presented with a history of gradual appearance of multiple nodules situated predominantly on the scalp and face. pathologic examination of...

Adnexal mass that can be suspected as malignant with ultrasonography diagnosed benign lesion at magnetic resonance imaging (MRI). This will help in preventing inappropriate surgery. MRI gives additional information on composition of soft-tissue masses using differences MR relaxation properties various tissue, which is not seen ultrasonography. To evaluate pelvic pathology by ultrasound and for ...

Background: Adnexal mass is a common clinical presentation among women of all age groups and extremely reproductive groups. It may be gynecological or non-gynecological origin. The exact prevalence adnexal could not determined, as most them develop resolve without any symptoms. poses special perplexity to the attending gynecologists, because differential diagnosis extensive masses are benign. D...

Abstract Background Swyer syndrome (Pure gonadal dysgenesis, 46 XY) is a rare form of disorder sexual development. These patients presented with external female phenotype, normal Mullerian structures and streak gonads. Pure XY are more likely to develop germ cell tumors due the presence Y chromosome. Case presentation A 19-year-old patient phenotype primary amenorrhea. Clinical examination, Kar...

Adnexal tumors (ATs) are primary skin tumors with benign or rarely, malignant behavior. They have been classified based on differentiation towards hair follicle, sebaceous, apocrine or eccrine gland. Few large-scale studies have focused on ATs. To determine the prevalence of ATs and to assess clinical and histopathological trend of ATs. A retrospective descriptive study of all ATs diagnosed in ...