BACKGROUND Diffuse large B-cell lymphoma sometimes involves the endocrine organs, but involvement of both the pituitary and adrenal glands is extremely rare. Involvement of these structures can lead to hypopituitarism and adrenal insufficiency, and subsequent recovery of their function is rarely seen. The present report describes an extremely rare case of pituitary and adrenal diffuse large B-c...

Adrenal glands are paired endocrine glands located over the upper renal poles. Adrenal pathologies have various clinical presentations. They can coexist with the hyperfunction of individual cortical zones or the medulla, insufficiency of the adrenal cortex or retained normal hormonal function. The most common adrenal masses are tumors incidentally detected in imaging examinations (ultrasound, t...

Coronavirus disease 2019 (COVID-19) has been associated with thrombotic and endocrine complications, including adrenal insufficiency in the setting of hemorrhage. We present a patient diagnosed antiphospholipid syndrome (APLS) COVID-19 infection resulting bilateral hemorrhage, subsequently leading to insufficiency. Acute hemorrhage is an underrecognized cause decompensation, multisystem failure...

By careful aseptic operation it was found possible to remove approximately three-quarters to seven-eighths of the adrenal tissue of guinea pigs without causing symptoms of adrenal insufficiency. Guinea pigs were immunized to Bacillus typhosus or to hen corpuscles at varying intervals before or after the operation, and the curves of antibody formation traced for 2 to 3 months after immunization....

The exposure of adult rats to oxygen at high pressure precipitates convulsive seizures.12 It seems that such exposures have an increased growth effect on the incisor3 and on the tooth germ of rat embryos in the uterus of mothers subjected to such seizures.4 In contrast, intermittent exposures to oxygen at atmospheric pressure promotes increased body weight of adult rats and embryos,3-5 but does...

Hepatic lipase activity is detectable in liver but also in adrenal glands, ovaries, and plasma. The subunit size of hepatic lipase in liver, adrenal glands, and nonheparin plasma was compared. Hepatic lipase in liver and adrenal glands appeared as a 55 kDa band. In liver, a faint band of lower size was also detected. In nonheparin plasma, hepatic lipase appeared as a doublet of 57 kDa and 59 kD...

Cushing’s disease is the term commonly used to identify a condition that results from the over-production of cortisol by the adrenal glands, two small glands located near the kidneys. Cortisol, a hormone that is important for regulating the metabolism of proteins, fats and carbohydrates, is produced by specialized cells comprising the outer or cortical portion of the adrenal glands. As a result...

We assessed the usefulness and reliability of computed tomography (CT scan) in evaluating adrenal hyperplasia in 38 patients, including 14 with Cushing's disease, 17 with idiopathic hyperaldosteronism (IHA), and 7 with the adrenogenital syndrome (AGS). Eighty-two normal subjects were also examined. We analyzed the shape of the adrenal gland and quantitated its thickness, width and length. Visua...

These studies were undertaken to determine the kinetic characteristics of high density lipoprotein (HDL) apo AI and cholesteryl ester transport in the hamster in vivo. Saturable HDL apo AI transport was demonstrated in the kidneys, adrenal glands, and liver. Saturable HDL cholesteryl ester transport was highest in the adrenal glands and liver. In the liver and adrenal glands, maximal transport ...