Electron microscope studies were carried out with the adrenocortical carcinoma 494 and normal adrenal cortex tissue. The mitochondria of the tumor cells showed marked differences when compared with mitochondria from fasciculata cells of the normal adrenal cortex. These differences were primarily related to mitochondrial number and crista structure. Corticosterone production in isolated tumor ce...

A 32-year-old woman who was followed for mammary adenoma every six months was found to have a left adrenal tumor on ultrasound examination in August 2016. She had no complaints and no abnormalities on physical examination. Blood analyses, including biochemical test and endocrinological test, were within normal values. However, 24-h urine collection showed modest elevation of catecholamines exce...

Corticomedullary mixed tumors of the adrenal gland are quite rare, with only five well-documented cases reported in the literature. Herein, we report the light microscopic and immunohistochemical features of two cases of this rare tumor. Patient 1 is a 34-year-old woman who presented with hypertension, hair loss, and amenorrhea of 1-year duration. Patient 2 is a 52-year-old woman who presented ...

A case is described involving a 71-year-old hirsute woman with a growing adrenal tumor and a high serum testosterone level, which did not normalize after adrenalectomy. Following this she was found to have a testosterone-producing ovarian Leydig cell tumor. This case provides key features that can help distinguish adrenal and ovarian causes of hirsutism.

Leiomyosarcoma is a malignant smooth muscle tumor. It the second most common primary retroperitoneal tumor behind liposarcoma. The léiomyosarcoma represents 11% of all tumors. age discovery between 40 and 60 years.