The process of re-entrainment and re-dispersion of powder particles is studied both theoretically and experimentally in order to discuss the possibilities of improvement of the quality of aerosol emitted from dry powder inhalers (DPI). The eddy fluid particle model (EFPM) is employed to solve turbulent flow structure in the microscale in a channel with various types of turbulence promoters. The...

When bacteria are disseminated into air, the concentration of viable cells in the aerosol decreases with time. It has been shown that part of this loss is due to impingement of cells on the surfaces of the container and to settling, but there is also considerable evidence for biological inactivation (Lester, 1948; Dunklin and Puck, 1948; Boyd and Forstat, 1953). This study has been undertaken t...

25 Stenotrophomonas maltophilia is a multi-drug resistant organism increasingly isolated from the 26 lungs of cystic fibrosis (CF) patients. One hundred twenty-five S. maltophilia isolates from 85 27 CF patients underwent planktonic and biofilm susceptibility testing against 9 different 28 antibiotics, alone and in double antibiotics combinations. When S. maltophilia were grown as a 29 biofilm,...

Irradiation of aerosols of either Escherichia coli or Serratia marcescens with simulated solar (xenon) radiation caused a significant decrease in viability. When sodium fluorescein was employed to determine the physical loss of organisms from the aerosol, an additional adverse effect upon survival was noted. The decay curves indicated that at least two mechanisms of inactivation were operative,...