PURPOSE To estimate the number of treatable eyes with neovascular subfoveal age-related macular degeneration (ARMD) in France. METHODS A literature search for studies documenting neovascular ARMD incidence rates and direct standardization according to age and gender were performed. Projection to the year 2025 was based on OECD (Organization for Economic and Co-operation Development) data. A c...

Younger and older adults were asked to saccade to an orientation-defined target that was presented alone, with a more central distractor, or with a more peripheral distractor. Both age groups exhibited saccadic averaging that was more pronounced in the central distractor condition, wherein older adults had the larger effect. These results are relevant to questions of oculomotor control and also...

Introduction: Age-related macular degeneration (ARMD) is the most common cause of visual impairment in people over 60 world. Forms of ARMD include the growth of new blood vessels underneath the retina (angiogenesis) and cystoid macular d which there is a loss of vision due to fluid-filled areas in the macular region. Anti-angiogenic substances like triamcinolo pegaptanib and bevacizumab have sh...

BACKGROUND Recent reports indicated that the slope of the foveal depression influences the macular pigment (MP) spatial profile. MP has been shown to confer possible protection against age-related macular degeneration (ARMD) because of its antioxidant properties. AIMS To study the configuration of foveal slope and the foveal thickness in fellow eyes of subjects with unilateral neovascular ARMD....

Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion (CRVO). Methods. Twelve patients from a single clinics day qualified for intravitreal injections (ARMD n = 6, DME n = 3, CRVO n = 3) and underwen...

PURPOSE It was proposed that total thiols (tSH) as powerful reducing agents and oxidized low-density lipoprotein (OX-LDL) may be associated with development of choroidal neovascularization in exudative age-related macular degeneration (E-ARMD). METHODS In a case-control study, 45 patients with E-ARMD were compared with 45 sex- and age-matched healthy controls. The levels of plasma homocystein...

The largest risk factor for age-related macular degeneration (ARMD) is advanced age. A prominent age-related change in the human retina is the accumulation of histochemically detectable neutral lipid in normal Bruch's membrane (BrM) throughout adulthood. This change has the potential to have a major impact on physiology of the retinal pigment epithelium (RPE). It occurs in the same compartment ...

Age-related macular degeneration (ARMD) is the main cause of vision loss in elderly inhabitants of industrialized countries. The most severe visual loss occurs in the wet or exudative form of ARMD. VEGF-inhibiting drugs administered through intravitreal injection, both ranibizumab (Lucentis® Genentech, South San Francisco, CA, USA), which was approved for this use, and bevacizumab (Avastin®, Ge...

OBJECTIVE To analyse satisfaction and patient preferences on the location where they receive an intravitreal injection. METHOD A survey was conducted with the intention of analysing these patients who attended the macula clinic and have been intervened using an intravitreal injection at least once in the day hospital or in the theatre setting, comparing both locations. RESULTS The majority ...

Macular pigment optical density (MPOD)-assessed using customized heterochromatic flicker photometry (cHFP)-is related to better cognition and brain lutein among adults. However, the reliability of MPOD assessed by cHFP has not been investigated in children. We assessed inter-session reliability of MPOD using modified cHFP. 7-10-year-olds (n = 66) underwent cHFP over 2 visits using 11 examiners....