Arm span and standing height were measured in 289 boys and 337 girls aged 6-15 years who were free from physical deformities which can affect stature or arm span. The arm span exceeded height in all age groups of boys and in older girls. At the age of 7, 11 and 12 years girls were significantly taller than the boys and had longer arm span while at the age of 15 years, the trend was opposite. Th...

BACKGROUND Mechanical valves and bioprostheses are widely used for aortic valve replacement. Though previous randomised studies indicate that there is no important difference in outcome after implantation with either type of valve, knowledge of outcomes after aortic valve replacement is incomplete. OBJECTIVE To predict age and sex specific outcomes of patients after aortic valve replacement w...

On Apr. 6, 1998, the US National Cancer Institute released preliminary results of the Breast Cancer Prevention Trial (BCPT). These results included a 45% reduction in the incidence of breast cancer among participants in the tamoxifen arm of the trial as compared with those in the placebo control arm. Scrutiny by the trial’s Endpoint Review, Safety Monitoring and Advisory Committee resulted in a...

We measured height and arm span of 400 males and 231 female subjects between 16-83 years of age. Arm span exceeded height in 82.6% subjects. Mean height to arm span ratio was 0.9711 and 0.9816 in males and females respectively, and was not significantly correlated with age. Linear regression equations were generated for both sexes for prediction of height from arm span and age. The use of heigh...

introduction diabetes is one of the chronic diseases. it is not curable but it can be controlled. the study aimed to determine the effect of family centered empowerment model on the treatment regime of school age children. materials and methods a clinical trial study was carried out on the school age diabetes children and their families. considering ethical matter a total of 50 diabetics patien...

Streptomyces linear chromosomes display various types of rearrangements after telomere deletion, including circularization, arm replacement, and amplification. We analyzed the new chromosomal deletion mutants Streptomyces griseus 301-22-L and 301-22-M. In these mutants, chromosomal arm replacement resulted in long terminal inverted repeats (TIRs) at both ends; different sizes were deleted again...

The Placement of Aortic Transcatheter Valves (PARTNER) trial randomized inoperable patients with severe symptomatic aortic stenosis (AS) to medical therapy versus transcatheter aortic valve replacement (TAVR) in 1 arm (PARTNER B) and high-surgical-risk AS patients to surgical aortic valve replacement (SAVR) versus TAVR in the other arm (PARTNER A).1,2 TAVR was far superior to medical therapy in...

Sequence-specific nucleases such as TALEN and the CRISPR/Cas9 system have so far been used to disrupt, correct or insert transgenes at precise locations in mammalian genomes. We demonstrate efficient 'knock-in' targeted replacement of multi-kilobase genes in human induced pluripotent stem cells (iPSC). Using a model system replacing endogenous human genes with their mouse counterpart, we perfor...

PURPOSE To evaluate the diagnostic potential of the electroretinogram (ERG) photostress test and the focal cone ERG in age-related maculopathy (ARM). METHODS The cohort comprised 31 patients with ARM and 27 age-matched control subjects. The ERG photostress test was used to monitor cone adaptation after intense light adaptation. Focal 41- and 5-Hz cone ERGs were recorded monocularly (central 2...