نتایج جستجو برای: aggressive multimodality
تعداد نتایج: 63355 فیلتر نتایج به سال:
INTRODUCTION Multimodality therapy with chemotherapy and operative resection is recommended for patients with locoregional pancreatic cancer but is not received by many patients. OBJECTIVE To evaluate patterns in the use and timing of chemotherapy and resection and factors associated with receipt of multimodality therapy in older patients with locoregional pancreatic cancer. METHODS We used...
Background B7-H3 positive tumors, including osteosarcoma, neuroblastoma, and high grade glioma, cause significant morbidity and mortality despite aggressive multimodality treatments. Current B7-H3-targeted immune-therapies take advantage of the monoclonal antibody 8H9, which is actively being evaluated in Phase I clinical trials. Engager T cells, which secrete bispecific engager molecules consi...
Thyroid carcinoma with distant metastases at initial presentation, is uncommon. Skull metastases occur very rarely, with a reported incidence of 2.5-5.8%. Here we report two cases of follicular thyroid cancer with skull involvement, and describe the diagnostic and therapeutic approach to metastatic thyroid cancer. We present the cases of a 70-year-old female and a 74-year-old female who present...
BACKGROUND Pancreatic adenocarcinoma is currently one of the deadliest cancers with high mortality rate. This disease leads to an aggressive local invasion and early metastases, and is poorly responsive to treatment with chemotherapy or chemo-radiotherapy. Radical resection is still the only curative treatment for pancreatic cancer, but it is generally accepted that a multimodality strategy is ...
Introduction/Background Although the overwhelming majority of nonmelanomatous and non-Merkel cell skin cancer (NMSC) of the head and neck, specifically basal cell carcinoma (BCC) and squamous cell carcinomas (SCC), is easily cured with surgical removal, superficial radiation therapy (RT), and/or ablation alone, there is a subset of these tumors— either due to neglect or unfavorable biological f...
objective: assessment of subgingival human cytomegalovirus (hcmv) and epstein barr virus (ebv-1) in subjects with aggressive periodontitis. materials and methods: samples were obtained from plaques formed in subgingival regions of 26 aggressive periodontitis patients. all specimens were submitted to polymerase chain reaction in order to detect hcmv and ebv-1. results: hcmv and ebv-1 were observ...
background: aggressive fibromatosis is a rare benign tumor with no potential for metastasis; however, its aggressive nature causes treatment failure and episodes of recurrence. there is no report from iran about the treatment of this tumor, and all published articles are single-case reports, therefore in this study, we report our experience from two of the largest referral centers of the south ...
background and aims. the aim of this study was to compare the effectiveness of adjunctive photodynamic therapy (pdt) in the treatment of aggressive periodontitis. materials and methods. a total of 24 patients with clinical diagnosis of aggressive periodontitis received scaling and root planing (srp) for periodontal treatment. in a split-mouth design study, the teeth of one quadrant of each arch...
PURPOSE To examine human performance and agreement on reticular pseudodrusen (RPD) detection and quantification by using single- and multimodality grading protocols and to describe and evaluate a machine learning system for the automatic detection and quantification of reticular pseudodrusen by using single- and multimodality information. METHODS Color fundus, fundus autofluoresence, and near...
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